Targeting SEZ6L2 in Colon Cancer: Efficacy of Bexarotene and Implications for Survival
Huajun Zheng,
Jianying Zheng,
Yan Shen
Abstract:BackgroundBexarotene, also recognized as Targretin, is categorized as a retinoid, a type of cancer drug. Nevertheless, the precise mechanisms of Bexarotene in relation to colon cancer remain unclear. In colon cancer, SEZ6L2 was suggested as one of the biomarkers and targets. This study presents a comprehensive exploration of the role of SEZ6L2 in colon cancer.MethodsWe utilized both TCGA data and a cohort of Chinese patients. In a meticulous analysis of 478 colon cancer cases, SEZ6L2 expression levels were exa… Show more
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