Targeting plasmid-encoded proteins that contain immunoglobulin-like domains to combat antimicrobial resistance
Alejandro Prieto,
Lluïsa Miró,
Yago Margolles
et al.
Abstract:Antimicrobial resistance (AMR) poses a significant threat to human health. Although vaccines have been developed to combat AMR, it has proven challenging to associate specific vaccine antigens with AMR. Bacterial plasmids play a crucial role in the transmission of AMR. Our recent research has identified a group of bacterial plasmids (specifically, IncHI plasmids) that encode large molecular mass proteins containing bacterial immunoglobulin-like domains. These proteins are found on the external surface of the b… Show more
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