Abstract:The goal of the research study was to shed light on a promising research area which may prove to be a safer more specific vaccine candidate; PfRH5 on merozoites. Erythrocyte invasion is paramount to the pathogenesis of P. falciparum requiring a series of extracellular recognition between the erythrocyte receptors and merozoites ligands. Of the known receptor-ligand interactions, one has been found essential to erythrocyte invasion in all P. falciparum strains; P. falciparum reticulocyte-binding protein homolog… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.