Targeting NADPH Oxidase as an Approach for Diabetic Bladder Dysfunction
Tammyris Helena Rebecchi Silveira,
Fábio Henrique Silva,
Warren G. Hill
et al.
Abstract:Diabetic bladder dysfunction (DBD) is the most prevalent complication of diabetes mellitus (DM), affecting >50% of all patients. Currently, no specific treatment is available for this condition. In the early stages of DBD, patients typically complain of frequent urination and often have difficulty sensing when their bladders are full. Over time, bladder function deteriorates to a decompensated state in which incontinence develops. Based on studies of diabetic changes in the eye, kidney, heart, and nerves, i… Show more
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