“…25 However, most of these inhibitors are small molecules that have undesirable biodistribution and poor tumor targeting capability. 26 Although loading them into nanocarriers may increase their tumor accumulation, the issue of burst release during circulation induces inevitable side effect, which endows the development of novel nanosystems for HIF-1α inhibitors delivery with great value. 27,28…”
Activatable photodynamic therapy (PDT) has shown great potential in cancer therapy owing to its high tumor specificity and minimized side effect. However, the relatively low level of biomarkers within tumor...
“…25 However, most of these inhibitors are small molecules that have undesirable biodistribution and poor tumor targeting capability. 26 Although loading them into nanocarriers may increase their tumor accumulation, the issue of burst release during circulation induces inevitable side effect, which endows the development of novel nanosystems for HIF-1α inhibitors delivery with great value. 27,28…”
Activatable photodynamic therapy (PDT) has shown great potential in cancer therapy owing to its high tumor specificity and minimized side effect. However, the relatively low level of biomarkers within tumor...
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