Targeting HER2-positive gastric cancer with a novel <sup>18</sup>F-labeled Z<sub>HER2:342</sub> probe

Pan, Yunyun; Yang, Zhengyang; Xu, Yuping; Bai, Zhicheng; Pan, Donghui; Yang, Ronghua; Wang, Lizhen; Guan, Wenxian; Yang, Min

doi:10.1039/c8ra10271f

Cited by 1 publication

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“…The performance of germanium materials can be enhanced through rare earth doping from multiple perspectives. In the last decade, numerous experimental and theoretical studies have been performed on transition metal and rare earth elements doped germanium clusters 24–39 . Zheng et al studied a series of gold‐doped Ge clusters by combining experimental photoelectron spectra (PES) with the density functional theory (DFT) theoretical calculation 24,26–28 .…”

Section: Introductionmentioning

confidence: 99%

Aromatic and magnetic properties in a series of heavy rare earth‐doped Ge₆ cluster anions

Zhang,

Wang,

et al. 2024

J Comput Chem

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A series of pentagonal bipyramidal anionic germanium clusters doped with heavy rare earth elements, (RE = Gd, Tb, Dy, Ho, Er, Tm, Yb, and Lu), have been identified at the PBE0/def2‐TZVP level using density functional theory (DFT). Our findings reveal that the centrally doped pentagonal ring structure demonstrates enhanced stability and heightened aromaticity due to its uniform bonding characteristics and a larger charge transfer region. Through natural population analysis and spin density diagrams, we observed a monotonic decrease in the magnetic moment from Gd to Yb. This is attributed to the decreasing number of unpaired electrons in the 4f orbitals of the heavy rare earth atoms. Interestingly, the system doped with Er atoms showed lower stability and anti‐aromaticity, likely due to the involvement of the 4f orbitals in bonding. Conversely, the systems doped with Gd and Tb atoms stood out for their high magnetism and stability, making them potential building blocks for rare earth‐doped semiconductor materials.

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Section: Introductionmentioning

confidence: 99%

Aromatic and magnetic properties in a series of heavy rare earth‐doped Ge₆ cluster anions

Zhang,

Wang,

et al. 2024

J Comput Chem

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Targeting HER2-positive gastric cancer with a novel ¹⁸F-labeled Z_HER2:342 probe

Abstract: Tumor targeting of the novel 18F-labeled ZHER2:342 probe in HER2-positive gastric cancer xenograft models.

Cited by 1 publication

References 36 publications

Aromatic and magnetic properties in a series of heavy rare earth‐doped Ge₆ cluster anions

Aromatic and magnetic properties in a series of heavy rare earth‐doped Ge₆ cluster anions

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Targeting HER2-positive gastric cancer with a novel 18F-labeled ZHER2:342 probe

Abstract: Tumor targeting of the novel 18F-labeled ZHER2:342 probe in HER2-positive gastric cancer xenograft models.

Cited by 1 publication

References 36 publications

Aromatic and magnetic properties in a series of heavy rare earth‐doped Ge6 cluster anions

Aromatic and magnetic properties in a series of heavy rare earth‐doped Ge6 cluster anions

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Targeting HER2-positive gastric cancer with a novel ¹⁸F-labeled Z_HER2:342 probe

Aromatic and magnetic properties in a series of heavy rare earth‐doped Ge₆ cluster anions

Aromatic and magnetic properties in a series of heavy rare earth‐doped Ge₆ cluster anions