Targeting CENPN to inhibit breast cancer progression: insights into cell growth and aerobic glycolysis modulation
Abstract:Breast cancer represents a significant health challenge for women globally. Although centromere protein N (CENPN) is reported to be upregulated in breast cancer, its detailed role remains unclear. This study used in silico analysis to investigate the expression profile and survival impact of CENPN in breast cancer. The CENPN level was evaluated using real-time quantitative polymerase chain reaction and western blot assays. The influence of CENPN on cell proliferation and aerobic glycolysis was investigated thr… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.