2022
DOI: 10.1038/s41587-022-01281-7
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Targeting a gene regulatory element enhances rice grain yield by decoupling panicle number and size

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Cited by 162 publications
(83 citation statements)
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“…In this study, we revealed that the functional differences of the two major GmST05 haplotypes resulted from natural variations in the promoter regions that affected their transcriptional level differences. Modulating the expression of important genes using genome editing will be a powerful approach for accelerating crop breeding (Hendelman et al., 2021; Wang et al., 2021; Song et al., 2022). Therefore, a modification of the transcription‐regulating regions of GmST05 may help us improve soybean yield.…”
Section: Discussionmentioning
confidence: 99%
“…In this study, we revealed that the functional differences of the two major GmST05 haplotypes resulted from natural variations in the promoter regions that affected their transcriptional level differences. Modulating the expression of important genes using genome editing will be a powerful approach for accelerating crop breeding (Hendelman et al., 2021; Wang et al., 2021; Song et al., 2022). Therefore, a modification of the transcription‐regulating regions of GmST05 may help us improve soybean yield.…”
Section: Discussionmentioning
confidence: 99%
“…7 a; Additional file 1 : Figure S6), stress-inducible promoters like RD29A and tissue-specific promoters from plant genes could be used instead of 35S promoter during genetic improvement of grapevine and other crops in the future. Recently, the CRISPR/Cas9 has been used to improve the crop traits by editing the regulatory elements/promoters of genes of interest [ 50 , 51 ]. Elevated ABA receptor expression could be achieved through promoter editing by using CRISPR/Cas9 technology.…”
Section: Discussionmentioning
confidence: 99%
“…To clone the genes underlying these loci, a chromosome segment substitution lines (CSSL) population should be constructed for the fine mapping of each related QTL [ 19 ]. Precise genome editing techniques will benefit the utilization of genes that control plant architecture in a selection of ideal varieties [ 42 ], provide strategies to reduce gene pleiotropy through the modification of cis -regulatory regions [ 43 ] or manipulate target genes for the de novo domestication of wild crop relatives [ 44 ].…”
Section: Discussionmentioning
confidence: 99%