Targeted testing in primary care demonstrates high prevalence of hepatitis B infection within the <scp>S</scp>lovak–<scp>R</scp>oma population in <scp>S</scp>heffield, <scp>UK</scp>

Gregory, Anthony; Vedio, Alicia; Stone, Brian; Green, S.; Bronsdon, C.

doi:10.1111/jvh.12287

Cited by 6 publications

(4 citation statements)

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“…A similar situation is observed for anti-HBc IgG positivity that is present in either chronic hepatitis B virus infection or after recovery from an acute hepatitis B infection. A overall higher prevalence of hepatitis B virus infection was observed in the Roma population in both children and adults when compared to the majority population and has been described in several studies [48][49][50].…”

Section: Discussionmentioning

confidence: 88%

The Roma Population Living in Segregated Settlements in Eastern Slovakia Has a Higher Prevalence of Metabolic Syndrome, Kidney Disease, Viral Hepatitis B and E, and Some Parasitic Diseases Compared to the Majority Population

Macejová

Kristián

Janíčko

et al. 2020

IJERPH

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Background: The Roma population is one of the largest marginalized population groups in Europe. The aim of our work was to summarize the morbidity of lifestyle-related diseases and infectious diseases in the Roma population living in segregated settlements. Methods: We used data from the cross-sectional study HepaMeta, in which we examined 452 Roma subjects with an average age of 34.7 ± 9.1 years, 35.2% of which were men, and 403 non-Roma subjects with an average age of 33.5 ± 7.4 years, 45.9% of which were men. We collected data by means of a questionnaire, anthropometric measures, and we analyzed blood and urine samples. Results: Roma subjects had a higher incidence of metabolic syndrome (RR: 1.478 (1.159–1.885), p < 0.0001), obesity or waist circumference >94 cm in men/80 cm in women (RR: 1.287 (1.127–1.470), p < 0.0001), and HDL-C < 1.03 mmol/L in men or <1.29 in women (RR: 2.004 (1.730–2.321), p < 0.0001) than their non-Roma counterparts. Subjects of the Roma population were more frequently diagnosed with kidney disease (RR: 1.216 (1.096–1.349), p < 0.0001), HBsAg positivity (RR: 4.468 (2.373–8.415), p < 0.0001), anti HBc IgG positivity (RR: 3.13 (2.598–4.224), p < 0.0001), and anti HEV positivity (RR: 2.972 (1.226–7.287), p < 0.0001). Serological markers of Toxoplasma gondii infection and Toxocara spp. were observed much more frequently among Roma than non-Roma subjects (RR: 1.868 (1.520–2.296), p < 0.0001, for Toxoplasma gondii; and RR: 21.812 (8.097–58.761), p < 0.0001, for Toxocara spp.). Conclusions: Poor socio-economic conditions, an unhealthy lifestyle, and barriers precluding access to healthcare are factors that affect the Roma population in settlements and lead to an increased prevalence of metabolic syndrome and its components, kidney disease, viral hepatitis B and E, and some parasitic diseases.

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Section: Discussionmentioning

confidence: 88%

The Roma Population Living in Segregated Settlements in Eastern Slovakia Has a Higher Prevalence of Metabolic Syndrome, Kidney Disease, Viral Hepatitis B and E, and Some Parasitic Diseases Compared to the Majority Population

Macejová

Kristián

Janíčko

et al. 2020

IJERPH

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“…It is significantly higher in tribal populations (11.9%) compared to non-tribal populations (3.1%) [ 18 ]. It is therefore no surprise that the Hepatitis B prevalence in all published studies was higher in Roma population, compared to non-Roma [ 2 , 19 , 20 , 21 ]. AntiHBc total or antiHBcIgG antibodies are positive in chronic Hepatitis B, however they also remain positive after an episode of acute Hepatitis B.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Risk Factors for Hepatitis B Virus Infection in Roma and Non-Roma People in Slovakia

Dražilová¹,

Janíčko

Kristián

et al. 2018

IJERPH

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Prevalence of Hepatitis B is relatively low in developed European countries. However specific subpopulations may exist within each country with markedly different Hepatitis B burden. Roma minority is very numerous in Slovakia and their lifestyle is completely different to non-Roma population. The aim of this study is to map Hepatitis B prevalence in Roma and compare it to non-Roma population and to explore potential socio-economic and health related risk factors. Cross-sectional epidemiology study was performed in Slovakia that included randomly sampled Roma population and geographically corresponding random sampled non-Roma population. Comprehensive questionnaire about risk factors was administered and blood samples were drawn for Hepatitis B serology and virology tests. Altogether 855 participants were included. Global Hepatitis B surface Antigen (HBsAg) positivity rate was 7.7% (i.e., active Hepatitis B) and anti Hepatitis B core IgG antibody (antiHBcIgG) positivity rate was 34.6%. Roma population had significantly higher prevalence of Hepatitis B, both active chronic infection (12.4%; 95% Confidence Interval (CI) 9.58%–15.97% versus 2.8%; 95% CI 1.56%–4.91%; p < 0.0001) and antiHBcIgG positivity (52.8%; 95% CI 48.17%–57.44% versus 25.9%; 95% CI 12.56%–20.02%; p < 0.0001) Main risk factors for HBsAg positivity were Roma ethnicity, male sex and tattoo. Conclusion: There is a very high prevalence of Hepatitis B in Roma communities in Slovakia, with potential for grave medical consequences.

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“…These communities experiences extreme health disparities, with a 10-year lower life expectancy than the settled population in the UK ( Equality and Human Rights Commission, 2017 ). HBV is not well studied among these populations, but in the UK a study of Roma people found a HBV surface antigen (HBsAg) prevalence of 9.4% and in Eastern Slovakia, Roma community members were four times more likely to be HBsAg-positive compared to the age-matched general population ( Macejova et al, 2020 ; Gregory et al, 2014 ). Risk factors associated with HBV infection included being male, older age, tattoos, and previous imprisonment ( Veselíny et al, 2014 ).…”

Section: Introductionmentioning

confidence: 99%

The forgotten people: Hepatitis B virus (HBV) infection as a priority for the inclusion health agenda

Martyn

Eisen

Longley

et al. 2023

eLife

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Hepatitis B virus (HBV) infection represents a significant global health threat, accounting for 300 million chronic infections and up to 1 million deaths each year. HBV disproportionately affects people who are under-served by health systems due to social exclusion, and can further amplify inequities through its impact on physical and mental health, relationship with stigma and discrimination, and economic costs. The ‘inclusion health’ agenda focuses on excluded and vulnerable populations, who often experience barriers to accessing healthcare, and are under-represented by research, resources, interventions, advocacy, and policy. In this article, we assimilate evidence to establish HBV on the inclusion health agenda, and consider how this view can inform provision of better approaches to diagnosis, treatment, and prevention. We suggest approaches to redress the unmet need for HBV interventions among excluded populations as an imperative to progress the global goal for the elimination of viral hepatitis as a public health threat.

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Targeted testing in primary care demonstrates high prevalence of hepatitis B infection within the Slovak–Roma population in Sheffield, UK

Cited by 6 publications

References 4 publications

The Roma Population Living in Segregated Settlements in Eastern Slovakia Has a Higher Prevalence of Metabolic Syndrome, Kidney Disease, Viral Hepatitis B and E, and Some Parasitic Diseases Compared to the Majority Population

The Roma Population Living in Segregated Settlements in Eastern Slovakia Has a Higher Prevalence of Metabolic Syndrome, Kidney Disease, Viral Hepatitis B and E, and Some Parasitic Diseases Compared to the Majority Population

Prevalence and Risk Factors for Hepatitis B Virus Infection in Roma and Non-Roma People in Slovakia

The forgotten people: Hepatitis B virus (HBV) infection as a priority for the inclusion health agenda

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