Targeted screening of high-risk cattle populations for BSE to augment mandatory reporting of clinical suspects

Doherr, Marcus G.; Heim, Dagmar; Fatzer, R; Cohen, C.; Vandevelde, M.; Zurbriggen, Andreas

doi:10.1016/s0167-5877(01)00203-3

Cited by 69 publications

(60 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although the largest numbers of tested cattle were healthy slaughtered cattle, the majority of positive cases occurred in the suspected cases and risk populations [29,47,48]. On average throughout the EU, the likelihood of finding BSE cases is more than 20 times higher in the risk populations than in healthy slaughtered cattle.…”

Section: Active Surveillancementioning

confidence: 98%

“…Because results of passive surveillance did not allow the true BSE prevalence to be estimated, in January 1999, Switzerland initiated an active, targeted surveillance scheme to enhance the detection of BSE cases in the adult cattle population [27,29]. In addition to the passive surveillance system, all cattle in the entire risk population (i.e., all cattle that have died or been killed on farm or during transport, fallen stock, and cattle sent to emergency/sick slaughter) over 24 months of age were tested.…”

Section: Active Surveillancementioning

confidence: 99%

Section: Active Surveillancementioning

confidence: 99%

“…Based on the results of active surveillance it could be demonstrated that the case ascertainment and case reporting levels during the time of passive surveillance were very low [20,29]. It could be demonstrated through retrospective investigations that more than half of the cases found by active surveillance had displayed clinical signs before death, either characteristic for BSE or at least sufficiently suggestive [18,29]. Also, comparing cases found by active and passive surveillance during the same period of time (passive surveillance takes place before death/slaughter) showed biases in the type of animals detected by passive surveillance, the ability to detect beef cow cases being far less efficient than detection of dairy cases [33].…”

Section: Active Surveillancementioning

confidence: 99%

See 3 more Smart Citations

Review on the epidemiology and dynamics of BSE epidemics

Ducrot¹,

et al. 2008

View full text Add to dashboard Cite

-The paper describes how the comprehensive surveillance of bovine spongiform encephalopathy (BSE) and studies carried out on these data has enhanced our knowledge of the epidemiology of BSE. Around 7 000 BSE cases were detected through the screening of about 50 million cattle with rapid tests in Europe. It confirmed that the clinical surveillance had a poor capacity to detect cases, and also showed the discrepancy of this passive surveillance efficiency between regions and production types (dairy/beef). Other risk factors for BSE were being in a dairy herd (three times more than beef), having a young age at first calving (for dairy cattle), being autumn-born (dairy and beef), and being in a herd with a very high milk yield. These findings focus the risk on the feeding regimen of calves/heifers. Several epidemiological studies across countries suggest that the feedborne source related to meat and bone meal (MBM) is the only substantiated route of infection -even after the feed ban -, while it is not possible to exclude maternal transmission or milk replacers as a source of some infections. In most European countries, the average age of the cases is increasing over time and the prevalence decreasing, which reflects the effectiveness of control measures. Consistent results on the trend of the epidemic were obtained using back-calculation modelling, the R 0 approach and Age-Period-Cohort models. Furthermore, active surveillance also resulted in the finding of atypical cases. These are distinct from previously found BSE and classified in two different forms based on biochemical characteristics; their prevalence is very low (36 cases up to 1st September 2007), affected animals were old and some of them displayed clinical signs. The origin and possibility of natural transmission is unknown.

show abstract

Section: Active Surveillancementioning

confidence: 98%

Section: Active Surveillancementioning

confidence: 99%

Section: Active Surveillancementioning

confidence: 99%

Section: Active Surveillancementioning

confidence: 99%

See 2 more Smart Citations

Review on the epidemiology and dynamics of BSE epidemics

Ducrot¹,

et al. 2008

View full text Add to dashboard Cite

show abstract

“…The decision was to apply from 1 January 2001. The decision was later amended to provide for testing of all fallen stock over 30 months of age (8).…”

Section: Phases In the Development Of Surveillance And Monitoringmentioning

confidence: 99%

Monitoring and analysis of bovine spongiform encephalopathy (BSE) testing in Denmark using statistical models

Paisley¹

2002

APMIS

View full text Add to dashboard Cite

PaisleyLG. Monitoring and analysis of bovine spongiform encephalopathy (BSE) testing in Denmark using statistical models. APMIS 2002;110:61-70.The evolution of monitoring and surveillance for bovine spongiform encephalopathy (BSE) from the phase of passive surveillance that began in the United Kingdom in 1988 until the present is described. Currently, surveillance for BSE in Europe consists of mass testing of cattle slaughtered for human consumption and cattle from certain groups considered to be at higher risk of having clinical or detectable BSE. The results of the ongoing BSE testing in Denmark have been analyzed using two statistical approaches: the ''classical'' frequentist and the Bayesian that is widely used in quantitative risk analysis. The analyses were intended to provide information for decision-makers, the media and the public as well as to provide inputs for future BSE surveillance models. The results to date suggest that the total number of BSE cases that will be found in Denmark in 2001 will not exceed 16.

show abstract

Surveillance and Monitoring Systems for Animal Health Programs and Disease Surveys

Salman

2003

Animal Disease Surveillance and Survey Systems

View full text Add to dashboard Cite

Targeted screening of high-risk cattle populations for BSE to augment mandatory reporting of clinical suspects

Cited by 69 publications

References 14 publications

Review on the epidemiology and dynamics of BSE epidemics

Review on the epidemiology and dynamics of BSE epidemics

Monitoring and analysis of bovine spongiform encephalopathy (BSE) testing in Denmark using statistical models

Surveillance and Monitoring Systems for Animal Health Programs and Disease Surveys

Contact Info

Product

Resources

About