Targeted magnetic iron oxide nanoparticles: Preparation, functionalization and biomedical application

Elrahman, Abeer A. Abd; Mansour, Fotouh R.

doi:10.1016/j.jddst.2019.05.030

Cited by 73 publications

(56 citation statements)

References 95 publications

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“…The use of polymers or surfactants is necessary to control particle size [ 70 ]. Furthermore, the size, shape, and magnetic properties of MNPs are influenced by the types and concentration of the salts, the pH and temperature of the medium, ionic strength, and mixing rate [ 59 , 70 ]. However, as MNPs obtained through co-precipitation have irregular shapes, wide size distribution, and low crystallinity, high-temperature synthesis methods are necessary to prepare high-quality MNPs [ 69 , 70 ].…”

Section: Magnetite Nanoparticles—synthesis Properties and Functimentioning

confidence: 99%

Magnetite Nanoparticles and Essential Oils Systems for Advanced Antibacterial Therapies

Mihai

Chircov

Grumezescu

et al. 2020

IJMS

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Essential oils (EOs) have attracted considerable interest in the past few years, with increasing evidence of their antibacterial, antiviral, antifungal, and insecticidal effects. However, as they are highly volatile, the administration of EOs to achieve the desired effects is challenging. Therefore, nanotechnology-based strategies for developing nanoscaled carriers for their efficient delivery might offer potential solutions. Owing to their biocompatibility, biodegradability, low toxicity, ability to target a tissue specifically, and primary structures that allow for the attachment of various therapeutics, magnetite nanoparticles (MNPs) are an example of such nanocarriers that could be used for the efficient delivery of EOs for antimicrobial therapies. The aim of this paper is to provide an overview of the use of EOs as antibacterial agents when coupled with magnetite nanoparticles (NPs), emphasizing the synthesis, properties and functionalization of such NPs to enhance their efficiency. In this manner, systems comprising EOs and MNPs could offer potential solutions that could overcome the challenges associated with biofilm formation on prosthetic devices and antibiotic-resistant bacteria by ensuring a controlled and sustained release of the antibacterial agents.

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Section: Magnetite Nanoparticles—synthesis Properties and Functimentioning

confidence: 99%

Magnetite Nanoparticles and Essential Oils Systems for Advanced Antibacterial Therapies

Mihai

Chircov

Grumezescu

et al. 2020

IJMS

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“…-advantage: effective production of small particle size (5-60 nm); -major drawbacks: sophisticated and expensive equipment, oxygen or other gaseous interferences; [32] New methods of producing MNPs which try to overcome the drawbacks of the established ones are periodically reported; however, for mass production of highly controlled features, MNPs, co-precipitation and thermal/hydrothermal decomposition remain the most secure and easy to use methods.…”

Section: Sol-gel Processesmentioning

confidence: 99%

Implication of Magnetic Nanoparticles in Cancer Detection, Screening and Treatment

2019

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During the last few decades, magnetic nanoparticles have been evaluated as promising materials in the field of cancer detection, screening, and treatment. Early diagnosis and screening of cancer may be achieved using magnetic nanoparticles either within the magnetic resonance imaging technique and/or sensing systems. These sensors are designed to selectively detect specific biomarkers, compounds that can be related to the onset or evolution of cancer, during and after the treatment of this widespread disease. Some of the particular properties of magnetic nanoparticles are extensively exploited in cancer therapy as drug delivery agents to selectively target the envisaged location by tailored in vivo manipulation using an external magnetic field. Furthermore, individualized treatment with antineoplastic drugs may be combined with magnetic resonance imaging to achieve an efficient therapy. This review summarizes the studies about the implications of magnetic nanoparticles in cancer diagnosis, treatment and drug delivery as well as prospects for future development and challenges of magnetic nanoparticles in the field of oncology.

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“…Magnetic particles of different size (nano-and micro-) and various composition resulting in different magnetization (superparamagnetic and ferromagnetic) have found numerous applications in biotechnology [1] and medicine [2][3][4][5]. Particularly, they are used for magneto-controlled targeting (delivering drugs [6,7], genes [8], radiopharmaceuticals [9]), in magnetic resonance imaging [10], in various diagnostic applications [11], for biosensing [12] (e.g., immunoassays [13]), RNA and DNA purification [14], gene cloning, cell separation and purification [15].…”

Section: Magnetic Nanoparticles-motivations and Applicationsmentioning

confidence: 99%

Synthesis, Properties and Applications of Magnetic Nanoparticles and Nanowires—A Brief Introduction

Katz

2019

Magnetochemistry

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Magnetic nanoparticles and magnetic nano-species of complex topology (e.g., nanorods, nanowires, nanotubes, etc.) are overviewed briefly in the paper, mostly giving attention to the synthetic details and particle composition (e.g., core-shell structures made of different materials). Some aspects related to applications of magnetic nano-species are briefly discussed. While not being a comprehensive review, the paper offers a large collection of references, particularly useful for newcomers in the research area.

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Targeted magnetic iron oxide nanoparticles: Preparation, functionalization and biomedical application

Cited by 73 publications

References 95 publications

Magnetite Nanoparticles and Essential Oils Systems for Advanced Antibacterial Therapies

Magnetite Nanoparticles and Essential Oils Systems for Advanced Antibacterial Therapies

Implication of Magnetic Nanoparticles in Cancer Detection, Screening and Treatment

Synthesis, Properties and Applications of Magnetic Nanoparticles and Nanowires—A Brief Introduction

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