Targeted Intermediates of Eudesmic Acid: Synthesis and X-ray Investigations

Abstract

It was carried out synthesis of esters and their dinitro derivatives of 3,4,5-trimethoxybenzoic (eudesmic) acid. Esterification of eudesmic acid carried out n absolute methanol or ethanol and corresponding methyl and ethyl 3,4,5-trimethoxybenzoates (have been synthesized in good yields. It was revealed that nitration of these esters gives only dinitro products. The structure of the synthesized compounds of the methyl and ethyl 2,6 trimethoxybenzoates (4, 5) was determined by X diffraction analysis (XRD). In the asymmetric part of the crystal structures of 4, 5 one and two molecules are observed, respectively. In crystalline structures a flat nitro groups and carboxylic groups do not participate in the conjugation with aromatic rings. I structure of 4, an intermolecular C8-H...O9 hydrogen bond is observed, these H bonds link the molecules along the [010] axis. In the crystal structure of intermolecular C9B-H...O4A and C10B hydrogen bonds form chains along the [011 formed chains are cross linked by the intermolecular C9B-H...O5A hydrogen bonds.