Targeted Endodontic Microsurgery: Computed Tomography–based Guided Stent Approach with Platelet-rich Fibrin Graft: A Report of 2 Cases

Popowicz, Witold; Palatyńska-Ulatowska, Aleksandra; Kohli, Meetu R.

doi:10.1016/j.joen.2019.08.012

Cited by 34 publications

(29 citation statements)

References 14 publications

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“…The recent years have seen a renewed interest in surgical guides (templates) for endodontic surgery, possibly because stereolithographic manufacturing (i.e. 3D printing) has become widely available and development in this direction has become a real possibility [8–10]. Patel et al, in a case report, described the use of a 3D printed custom retractor for endodontic surgery [11].…”

Section: Introductionmentioning

confidence: 99%

Accuracy and clinical safety of guided root end resection with a trephine: a case series

Antal

Nagy

Braunitzer³

et al. 2019

Head Face Med

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BackgroundRoot-end resection is an endodontic surgical intervention that requires high precision so that all ramifications and lateral canals so as infected tissues are eliminated. An exploratory study was conducted to justify the clinical safety and accuracy of guided root-end resection with a trephine.MethodsFourteen root-end resections were performed in 11 patients. With the aid of computer tomography and rapid prototyping a stereolithographically fabricated, tooth-supported surgical template was used to guide trephinations. Surgery was performed using the printed surgical stent and a trephine was used not only for the osteotomy but for the root end resection as well.ResultsThe root end was successfully and completely resected by the trephine in all cases. No intraoperative complications were observed in any of the cases, and the patients were free of symptoms indicating recurrence or complications at the 6-month follow-up. The median angular deviation of the trephination was 3.95° (95% CI: 2.1–5.9), comparable to the angular deviation of guided implant surgery. The mean apex removal error (ARE) was 0.19 mm (95% CI: 0.03–0.07). The mean osteotomy depth error (ODE) was 0.37 mm (95% CI: 0.15–1.35). Overpenetration was a characteristic finding, which indicates the necessity of a stop-trephine.ConclusionsWithin the limitations of this study, we conclude that our results support the use of guided trephination for root-end resection.

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Section: Introductionmentioning

confidence: 99%

Accuracy and clinical safety of guided root end resection with a trephine: a case series

Antal

Nagy

Braunitzer³

et al. 2019

Head Face Med

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“…The use of PRF to improve the healing of endodontic lesion was successfully documented in recent literature by Popowicz et al, with 2 case reports at 1-year follow up [ 13 ], and also by Goyal et al with 3 case reports in a study in March 2020 [ 14 ]. However, in larger studies where the use of PRP was added to endodontic surgery, the difference in terms of bone quality compared to that of the control group was not statistically significant [ 15 ].…”

Section: Discussionmentioning

confidence: 99%

B.P.F.C.® Bio-Plasma® with Pure Growth Factors (BioPlasma®) Used for the Treatment of a Persistent Great Periapical Lesion of an Endodontically Treated Tooth: A New Therapeutic Option

Viganò

Disconzi

Bertini

et al. 2020

Case Reports in Dentistry

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The aim of this case report was to evaluate the efficacy of a new platelet-rich plasma preparation and its regenerative capacity of bone periapical tissue for the treatment of a very compromised endodontic treated tooth, with a periapical lesion of 1.5 cm in diameter, using a pure platelet concentrate. This is made without the use of anticoagulant or any type of activator, e.g., bovine thrombin, calcium chloride. For this reason, it has been called “Pure”; it is the B.P.F.C.® Bio-Plasma® with Pure Growth Factors (BioPlasma®) designed and developed by Dr. Raffaello Viganò. The patient has read and signed a written consent form. The study protocol was approved by the Ethics Committee for Human Studies, University of Varese. X-ray at 2 and 6 months and 4 years after endodontic surgery demonstrated the success of the treatment.

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“…Of the seven articles included, three were experimental trials [14][15][16], three were CS [17][18][19] and one was a clinical trial (CT) [20]. In addition, three studies compared static navigation with regard to conventional endodontic microsurgery [14][15][16].…”

Section: Qualitative Analysismentioning

confidence: 99%

“…Experimental trials presented a sample size ranging from 42 in the study by Fan, 2019 [15] to the high figure of 110 in Pinsky's study, 2007 [16]. However, most clinical studies were CS with two to three patients [17][18][19] and only one CT was included with a sample size of 14 apicoectomies in 13 teeth of 11 patients [16] (Table 1).…”

Section: Qualitative Analysismentioning

confidence: 99%

“…The results of methodological quality assessment using the Jadad scale are shown in Table 3. The Jadad scale obtained tree articles "not applicable", because they were a case series [17][18][19], and the authors of these articles did not blind and did not randomize the studies. In addition, the CT study [20] was also described as "not applicable", because it was not a comparative study and the authors did not randomize the study.…”

Section: Quality Assessmentmentioning

confidence: 99%

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Efficacy of Computer-Aided Static Navigation Technique on the Accuracy of Endodontic Microsurgery. A Systematic Review and Meta-Analysis

Zubizarreta-Macho

Castillo-Amature

Montiel-Company

et al. 2021

JCM

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The aim of this systematic review and meta-analysis was to analyze the efficacy of the computer-aided static navigation technique on the accuracy of root apex location in endodontic microsurgery. Material and Methods: A systematic literature review and meta-analysis, based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations, of clinical studies that evaluated the apex location rate of the computer-aided static navigation techniques applied to endodontic microsurgery. A total of four databases were consulted in the literature search: Pubmed-Medline, Scopus, Cochrane, and Web of Science. After eliminating duplicated articles and applying the inclusion criteria, seven articles were selected for the qualitative and the quantitative analysis. Results: The root apex location success rate stated at 96.8% (confidence interval (CI): 93.0–100%) of the cases performed through a computer-aided static navigation technique. The prediction interval ranges from 91.4% to 100%. The meta-analysis did not detect heterogeneity between the combined studies (Q-test = 6.15; p-value = 0.407; I2 = 2.4%). The computer-aided static navigation techniques showed a root apex location success rate 27 times higher than conventional endodontic microsurgery procedures (Q test = 0.80; p = 0.671; I2 = 0%). Three studies of computer-aided static navigation techniques and control group were compared using a random effects model with the Mantel-Haenszel method with a statistically significant odds success ratio of 27.7, with a 95% confidence interval between 11.3 and 68.1 (z test = 7.23; p < 0.0001). Conclusions: According to in vitro studies analyzed, endodontic microsurgeries performed through computer-aided static navigation techniques show a high precision.

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Targeted Endodontic Microsurgery: Computed Tomography–based Guided Stent Approach with Platelet-rich Fibrin Graft: A Report of 2 Cases

Cited by 34 publications

References 14 publications

Accuracy and clinical safety of guided root end resection with a trephine: a case series

Accuracy and clinical safety of guided root end resection with a trephine: a case series

B.P.F.C.® Bio-Plasma® with Pure Growth Factors (BioPlasma®) Used for the Treatment of a Persistent Great Periapical Lesion of an Endodontically Treated Tooth: A New Therapeutic Option

Efficacy of Computer-Aided Static Navigation Technique on the Accuracy of Endodontic Microsurgery. A Systematic Review and Meta-Analysis

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