Abstract:Breast cancer is one of the serious diseases and has the second-highest
mortality in women worldwide. RNA interference has been developed as a
promising way of specific cancer treatment by silencing oncogenes
efficiently. However, small RNAs exhibits difficulties in specific
cellular uptake and instability. Therefore, we designed novel fusion
peptides (RS and RT) for an efficient, stable, and specific delivery of
small RNAs. Both RS and RT peptides could form self-assembled
nanocomplexes via electrostatic attr… Show more
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