Targeted Antibacterial Therapy: Ag Nanoparticles Cluster with pH‐Triggered Reassembly in Targeting Antimicrobial Applications (Adv. Funct. Mater. 17/2020)

Xie, Xianli; Sun, Tian-Ci; Xue, Jingzhe; Miao, Zhaohua; Xu, Yan; Fang, Wei; Li, Qing; Tang, Rupei; Lü, Yang; Tang, Longxiang; Zha, Zhengbao; He, Tao

doi:10.1002/adfm.202070106

Cited by 8 publications

(6 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Betaine and AgNPs effectively suppress and kill bacteria, thereby conferring the NSD-Gel e-skin with highly effective antibacterial properties (Figure 1a). [47][48][49] To minimize freezing and drying, which occur in conventional hydrogels, the binary solvent and zwitterion were used as media and functional filler, respectively, which lowers the freezing temperature by interrupting the hydrogen bonds in ice crystals and slows the rate of drying by reducing vapor pressure (Figure 1b,c). [50][51] Moreover, the Na + , H + , and AgNPs in the solvent make the NSD-Gel e-skin conductive, and the NSD-Gel e-skin possesses hypersensitivity to strain due to deformation can effectively change the ion transport path and time (Figure 1d).…”

Section: Design and Fabrication Of Nsd-gel E-skinmentioning

confidence: 99%

Mechanically Robust and Transparent Organohydrogel‐Based E‐Skin Nanoengineered from Natural Skin

Bai

Wang

Zheng

et al. 2023

Adv Funct Materials

View full text Add to dashboard Cite

Electronic skins (e‐skins), which are mechanically compliant with human skin, are regarded as ideal electronic devices for noninvasive human–machine interaction and wearable devices. In order to fully mimic human skin, e‐skins should possess reliable mechanical properties and be able to resist external environmental factors like heat, cold, desiccation, and bacteria, while perceiving multiple external stimuli, such as temperature, humidity, and strain. Here, a transparent, mechanically robust, environmentally stable, versatile natural skin‐derived organohydrogel (NSD‐Gel) is nanoengineered through the integration of betaine, silver nanoparticles, and sodium chloride in a glycerol/water binary solvent. The transparent NSD‐Gel e‐skin exhibits outstanding tensile strength (7.33 MPa), puncture resistance, moisture retention, self‐regeneration, and antibacterial properties. Additionally, the NSD‐Gel e‐skin possesses enhanced cold/heat resistance and stimuli‐responsive characteristics that effectively sense environmental temperature and humidity changes, as well as physiological human body motion signals. In vitro and in vivo experiments show that the NSD‐Gel e‐skin confers desired biocompatibility and tissue protective properties even in extremely harsh environments (−196 °C to 100 °C). The NSD‐Gel e‐skin has great potential for applications in multidimensional wearable electronic devices, human‐machine interfaces, and artificial intelligence, generating a versatile platform for the development of high‐performance e‐skins with on‐demand properties.

show abstract

Section: Design and Fabrication Of Nsd-gel E-skinmentioning

confidence: 99%

Mechanically Robust and Transparent Organohydrogel‐Based E‐Skin Nanoengineered from Natural Skin

Bai

Wang

Zheng

et al. 2023

Adv Funct Materials

View full text Add to dashboard Cite

show abstract

“…[ 46 ] The current clinical dressings used to inhibit wound infection usually depend on the delivery of small‐molecule drugs. [ 47 ] However, uncontrolled drug release can easily generate drug‐resistant bacteria, and the cumulative drug toxicity can inhibit the normal wound healing process. [ 46,48 ] To solve these problems, we developed a chitosan‐based self‐antibacterial quaternary ammonium salt, which, as an antibacterial macromolecule, can effectively facilitate the controllable drug release and thus increase the long‐term antibacterial ability.…”

Section: Resultsmentioning

confidence: 99%

Flexible Bicolorimetric Polyacrylamide/Chitosan Hydrogels for Smart Real‐Time Monitoring and Promotion of Wound Healing

Zheng

Tong

Zhang

et al. 2021

Adv Funct Materials

162

106

View full text Add to dashboard Cite

Real‐time monitoring of wound healing remains a major challenge in clinical tissue regeneration, calling the need for the development of biomaterial‐guided on‐site monitoring wound healing technology. In this study, multifunctional double colorimetry‐integrated polyacrylamide‐quaternary ammonium chitosan‐carbon quantum dots (CQDs)‐phenol red hydrogels are presented, aiming to simultaneously detect the wound pH level, reduce bacterial infection, and promote wound healing. The hybridization of CQDs and pH indicator (phenol red) with the hydrogels enables their high responsiveness, reversibility, and accurate indication of pH variability to reflect the dynamic wound status in the context of both ultraviolet and visible light. Furthermore, these visual images can be collected by smartphones and converted into on‐site wound pH signals, allowing for a real‐time evaluation of the wound dynamic conditions in a remote approach. Notably, the hydrogels exhibit excellent hemostatic and adhesive properties, maintain sufficient wound moisture, and promote wound healing via their high antibacterial activity (against Staphylococcus Aureus, and Escherichia Coli) and skin repair function. Overall, the resulting hydrogels have high potential as a novel smart and flexible wound dressing platform for theranostic skin regeneration.

show abstract

“…[11] Recently, people have evolved to exploit nanomaterials as an alternative to combat bacterial infection, including antibacterial nanomaterials. [9] Up to date, noble metal (e.g., Ag [12] and Au [13] ) nanoparticles and metal oxide (e.g., ZnO, [14] CuO, [15] and TiO 2 , [16] ) nanoparticles have been employed as antimicrobial reagents, attributable to the associated reactive ion release, photocatalytic activity, reactive oxygen species (ROS) generation, and/or physical contact with bacterial cells. [17] However, most of these nanomaterials are associated with high production expenses and/or the potential emission of toxic substances that can pose a health threat to human beings and the nature.…”

Section: Introductionmentioning

confidence: 99%

Shining light on carbon dots: Toward enhanced antibacterial activity for biofilm disruption

Zhang,

Fu,

Lin

et al. 2024

Biotechnology Journal

View full text Add to dashboard Cite

In spite of tremendous efforts dedicated to addressing bacterial infections and biofilm formation, the post‐antibiotic ear continues to witness a gap between the established materials and an easily accessible yet biocompatible antibacterial reagent. Here we show carbon dots (CDs) synthesized via a single hydrothermal process can afford promising antibacterial activity that can be further enhanced by exposure to light. By using citric acid and polyethyleneimine as the precursors, the photoluminescence CDs can be produced within a one‐pot, one‐step hydrothermal reaction in only 2 h. The CDs demonstrate robust antibacterial properties against both Gram‐positive and Gram‐negative bacteria and, notably, a considerable enhancement of antibacterial effect can be observed upon photo‐irradiation. Mechanistic insights reveal that the CDs generate singlet oxygen (1O2) when exposed to light, leading to an augmented reactive oxygen species level. The approach for disruption of biofilms and inhibition of biofilm formation by using the CDs has also been established. Our findings present a potential solution to combat antibacterial resistance and offer a path to reduce dependence on traditional antibiotics.

show abstract

Targeted Antibacterial Therapy: Ag Nanoparticles Cluster with pH‐Triggered Reassembly in Targeting Antimicrobial Applications (Adv. Funct. Mater. 17/2020)

Cited by 8 publications

References 0 publications

Mechanically Robust and Transparent Organohydrogel‐Based E‐Skin Nanoengineered from Natural Skin

Mechanically Robust and Transparent Organohydrogel‐Based E‐Skin Nanoengineered from Natural Skin

Flexible Bicolorimetric Polyacrylamide/Chitosan Hydrogels for Smart Real‐Time Monitoring and Promotion of Wound Healing

Shining light on carbon dots: Toward enhanced antibacterial activity for biofilm disruption

Contact Info

Product

Resources

About