Abstract:HSP70s constitute a family of chaperones, some isoforms of which appear to play a role in sperm function. Notably, global proteomic studies analysing proteins deregulated in asthenozoospermia, a main cause of male infertility characterized by low sperm motility, showed the deregulation of some HSP70 isoforms. However, to date, no clear trend has been established since the variations in the abundance of HSP70 isoforms differed between studies. The HSPA2 isoform has been reported to play a key role for fertiliza… Show more
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