2024
DOI: 10.1002/ptr.8221
|View full text |Cite
|
Sign up to set email alerts
|

Taraxerone exerts antipulmonary fibrosis effect through Smad signaling pathway and antioxidant stress response in a Sirtuin1‐dependent manner

Ziwei Chen,
Weixi Xie,
Siyuan Tang
et al.

Abstract: Idiopathic pulmonary fibrosis treatments are limited, often with severe side effects, highlighting the need for novel options. Taraxerone has diverse biomedical properties, but its mechanism remains unclear. This study investigates taraxerone's impact and the mechanisms involved in bleomycin‐induced pulmonary fibrosis in mice. After establishing a pulmonary fibrosis mouse model, taraxerone was intraperitoneally injected continuously for 14–28 days. The in vivo antifibrotic and antioxidative stress effects of t… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 60 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?