On March 16 2020, President Trump introduced strict social distancing guidelines for the United States, in an effort to stem the spread of the COVID-19 pandemic. This had an immediate major effect on the job market, with millions of Americans forced to find alternative ways to make a living from home. Here, we investigate the possibility that this policy also changed the pool of workers available to take part in academic studies on Amazon Mechanical Turk (MTurk) – either by influencing which existing MTurk workers participate, or by causing an influx of new ones. Specifically, we look at 10,510 responses gathered in 16 studies run between February 25, 2020, and May 14, 2020, examining the distribution of gender, age, ethnicity, political preferences, and analytic cognitive style. We find important changes on all measures following the imposition of nationwide social distancing: participants are more substantially less reflective (as measured by the Cognitive Reflection Test, CRT) and more Republican, and somewhat less likely to be white and experienced with MTurk. Most of these differences are explained by an influx of new participants who are somewhat less attentive than, and demographically different from, previous participants.