Tapioca melanoma of the iris

Pick, Zelda S; Wilson, Graham

doi:10.1111/j.1444-0938.2008.00344.x

Cited by 5 publications

(5 citation statements)

References 9 publications

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“…S-100 marker is usually used to stain melanoma and neural tissues, while Ki-67 and HMB-45 are used to mark proliferating cells. [1,8] In the present case, immunostaining was positive for S-100, HMB-45, Ki-67, and melan-A that confirmed the diagnosis of iris melanoma.…”

Section: Discussionsupporting

confidence: 76%

“…[3] Compared to the other types of iris melanoma, tapioca melanoma mostly occurs in younger patients. [1] The youngest reported case was that of a seven-year-old patient. [3] There could be a connection between the inception of hormonal changes at puberty and the commencement of uveal melanoma.…”

Section: Discussionmentioning

confidence: 99%

“…[6] Diseases such as Fuch's heterochromic iridocyclitis, neurofibromatosis, and Cogan-Reese may present with iris nodules and elevated IOP. [1] In neurofibromatosis, there are yellow-brown dome-shaped papules on the iris called Lisch nodules, while Cogan-Reese presents irregular corneal endothelium with pedunculated and pigmented nodules. In sarcoidosis, patients have systemic signs and symptoms along with papillitis, papilledema, and granulomas in any part of the eye.…”

Section: Discussionmentioning

confidence: 99%

“…In conclusion, tapioca iris melanoma should be considered in differential diagnosis of any iris tumor presenting as a nodular vascularized iris mass and elevated IOP. [1] Brachytherapy with ruthenium-106 plaque would be a useful treatment for tapioca iris melanoma.…”

Section: Discussionmentioning

confidence: 99%

“…Tapioca melanoma of the iris is a rare form of diffuse iris melanoma, [1,2] typically presenting with heterochromia and elevated intraocular pressure (IOP), mainly because of aqueous outflow blockade. This tumor could also manifest as a diffuse, circumferential, and lightly pigmented or amelanotic lesion.…”

Section: Introductionmentioning

confidence: 99%

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Tapioca Melanoma of the Iris: a Case Report

Karimi

Pahlevani

2019

JOVR

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PurposeTo report an extremely rare case of tapioca melanoma of the iris in an Iranian patient.Case ReportA 50-year-old male patient presented with ocular pain and redness in the right eye for two weeks. The visual acuity was 7/10 and the intraocular pressure (IOP) was 30 mmHg. A lobulated amelanotic vascularized and nodular (tapioca-like) iris mass with a 180o extent was seen in the right eye. Incisional biopsy of the mass revealed atypical mixed type (epithelioid and spindle cell) melanoma. Brachytherapy with the ruthenium-106 plaque resulted in complete regression of the tumor.ConclusionTapioca melanoma of the iris should be considered in the differential diagnosis of patients presenting with nodular vascularized amelanotic iris mass and elevated IOP. Brachytherapy with ruthenium-106 seems to be an effective treatment for tapioca melanoma of the iris.

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Section: Discussionsupporting

confidence: 76%