2022
DOI: 10.3389/fpls.2022.979678
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Tap the sap – investigation of latex-bearing plants in the search of potential anticancer biopharmaceuticals

Abstract: Latex-bearing plants have been in the research spotlight for the past couple of decades. Since ancient times their extracts have been used in folk medicine to treat various illnesses. Currently they serve as promising candidates for cancer treatment. Up to date there have been several in vitro and in vivo studies related to the topic of cytotoxicity and anticancer activity of extracts from latex-bearing plants towards various cell types. The number of clinical studies still remains scarce, however, over the ye… Show more

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“…18 Typical families include Euphorbiaceae, Asteraceae, Apocyna- ceae, and Papaveraceae. 19,20 Laticiferous species are more frequently observed in tropical than in temperate regions. 18 The metabolite composition across different latex-bearing plants varies, with a range of diverse chemical compounds, like alkaloids (Papaveraceae, e.g., Macleaya cordata, Papaver somniferum, Chelidonium majus), terpenoids (Euphorbiaceae, e.g., Hevea brasiliensis), phenolic glucosides (Cannabaceae, e.g., Cannabis sativa), or cardenolides (Asclepiadaceae, e.g., Asclepias curassavica).…”
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confidence: 99%
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“…18 Typical families include Euphorbiaceae, Asteraceae, Apocyna- ceae, and Papaveraceae. 19,20 Laticiferous species are more frequently observed in tropical than in temperate regions. 18 The metabolite composition across different latex-bearing plants varies, with a range of diverse chemical compounds, like alkaloids (Papaveraceae, e.g., Macleaya cordata, Papaver somniferum, Chelidonium majus), terpenoids (Euphorbiaceae, e.g., Hevea brasiliensis), phenolic glucosides (Cannabaceae, e.g., Cannabis sativa), or cardenolides (Asclepiadaceae, e.g., Asclepias curassavica).…”
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confidence: 99%
“…Latex-bearing plants have been a compelling source of bioactive compounds for the past few decades, drawing attention due to their antimicrobial to anticancer activities. It is a very diverse group of more than 20,000 plant species across over 40 families of angiosperm plants . Typical families include Euphorbiaceae, Asteraceae, Apocynaceae, and Papaveraceae. , Laticiferous species are more frequently observed in tropical than in temperate regions . The metabolite composition across different latex-bearing plants varies, with a range of diverse chemical compounds, like alkaloids (Papaveraceae, e.g., Macleaya cordata , Papaver somniferum , Chelidonium majus ), terpenoids (Euphorbiaceae, e.g., Hevea brasiliensis ), phenolic glucosides (Cannabaceae, e.g., Cannabis sativa ), or cardenolides (Asclepiadaceae, e.g., Asclepias curassavica ) .…”
mentioning
confidence: 99%