Tannic acid intoxication in sheep and mice

Zhu, Jiayin; Filippich, L. J.; Alsalami, M.T.

doi:10.1016/0034-5288(92)90128-o

Cited by 71 publications

(65 citation statements)

References 21 publications

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“…In a study that compared TA and oak leaves with comparable amounts of tannins, feeding oak leaves caused severe damage to the animal compared with TA (Plumlee et al, 1998). Oral administration of TA did not produce liver damage as evidenced in either blood parameters, which is consistent with other findings Filippich, 1992 andPlumlee et al, 1998) and confirmed by histological studies (Plumlee et al, 1998). The reason for the absence of liver damage in sheep following high levels of TA feeding is not entirely clear, although several factors may be involved.…”

Section: Discussionsupporting

confidence: 78%

“…One study reported the absence of pyrogallol after dosing calves with TA (Plumlee et al, 1998). Serum biochemistry was within the range that was reported by other authors (Zhu and Filippich, 1992;Plumlee et al, 1998). Only blood urea-N was affected by both the level of tannin and sampling time after feeding, although other metabolites were affected by sampling time.…”

Section: Discussionsupporting

confidence: 63%

“…Due to its availability, cost and relative purity, tannic acid has been used widely to study the effect of tannins on rumen fermentation (Driedger et al, 1969;Nishimuta et al, 1974;Murdiati et al, 1992;Zhu and Filippich, 1992;Plumlee et al, 1998;Hervas et al, 2000;Santos et al, 2000;Frutos et al, 2004;Martinez et al, 2005 and. The objective of this study was to assess the influence of spraying tannic acid (TA) on chopped alfalfa hay on in vitro rumen fermentation of dry matter (DM) and N retention by sheep fed alfalfa hay.…”

Section: Introductionmentioning

confidence: 99%

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Influence of tannic acid application on alfalfa hay: in vitro rumen fermentation, serum metabolites and nitrogen balance in sheep

Getachew¹,

Pittroff

DePeters

et al. 2008

Animal

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Alfalfa protein is poorly utilised by ruminants due to its rapid degradation in rumen. The objective of the study was to assess the influence of spraying tannic acid (TA) on chopped alfalfa hay on in vitro rumen fermentation and nitrogen (N) retention by sheep. Alfalfa hay with and without TA was fed to sheep to determine nutrient digestibility and N balance. TA was sprayed on chopped alfalfa at three concentrations to determine its effect on in vitro fermentation of dry matter (DM) and N balance in sheep. Final TA concentrations were 0, 30, 60 and 90 g TA per kg DM. The control was sprayed with the same amount of water but without TA. In vitro DM degradation and the production of gas, ammonium-N (NH 4 -N) and short-chain fatty acid (SCFA) were measured. TA-sprayed alfalfa and the control were fed to sheep to determine nutrient digestibility and N retention. Addition of TA had no influence on the extent and rate of gas production but significantly decreased NH 4 -N concentration at 30 (P , 0.05), 60 and 90 (P , 0.0001) g/kg DM. Addition of polyethylene glycol (PEG) to TA-sprayed alfalfa increased NH 4 -N to a level comparable to non-TA-sprayed alfalfa. Spraying of alfalfa with TA significantly decreased (P , 0.05) isovalerate but did not affect the total and individual SCFA acid production. Tannic acid significantly (P , 0.05) reduced in vitro true degradability of DM (IVTD) after 24 h incubation at levels of 60 and 90 g TA per kg DM. Neutral-detergent fibre digestibility (dNDF) after 24 h (P , 0.01), 60 and 90 (P , 0.0001) g TA per kg DM. The effect of TA on either IVTD or dNDF was not significant (P . 0.05) after 48 h of incubation. There was a strong linear relationship between percentage increase in gas production due to PEG and protein precipitation capacity (R 2 5 0.94). N digestibility was significantly reduced with all three levels of TA additions. However, the proportion of urine-N to total N output was reduced by adding 60 g (P , 0.05) and 90 g (P , 0.01) TA per kg DM. Serum metabolites and liver enzymes were not affected by TA (P . 0.05). Higher faecal N as the TA level increased indicates incomplete dissociation of tannin-protein complexes post ruminally. Factors affecting dissociation of tannin-protein complexes need further study.

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Section: Discussionsupporting

confidence: 78%

Section: Discussionsupporting

confidence: 63%

Section: Introductionmentioning

confidence: 99%

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Influence of tannic acid application on alfalfa hay: in vitro rumen fermentation, serum metabolites and nitrogen balance in sheep

Getachew¹,

Pittroff

DePeters

et al. 2008

Animal

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“…The two classes of tanninshydrolysable (HT) and condensed (CT)-are generally regarded as anti-nutritional factors for ruminants, as they form complexes with proteins, including enzymes (Goel et al, 2005a, b), resulting in a remarkable reduction in the biodegradation of the fibrolytic polymers in the rumen, feed intake and dry matter digestibility (McSweeney et al, 2001). Tannic acid (TA), a typical hydrolysable tannin, is even toxic to both ruminant and monogastrics, particularly when it is available in the diets of those animals in excessive amounts (Zhu et al, 1992). However, ruminants have developed an adaptation mechanism against tannins via a microbial ecosystem inhabiting in their gastrointestinal tract (Goel et al, 2005a).…”

Section: Treatment Compositionmentioning

confidence: 99%

Anaerobic degradation of tannins in <i>Acacia nilotica</i> pods by <i>Enterococcus faecalis</i> in co-culture with ruminal microbiota

Goel

Raghav

Beniwal

et al. 2015

J. Gen. Appl. Microbiol.

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“…No significant changes in plasma enzymes AST and GGT were found. These enzymes are used to detect if tannin-related hepatotoxicity occurred (Zhu & Filippish, 1992 fed with lucerne hay, the blood urea nitrogen concentration was higher (P ≤ 0.05) than in sheep fed with the diets where vine husks and pips were included, which is directly related to the limitation in protein digestibility in sheep fed vine husks and pips. The digestibility of the CP, NDF and ADF decreased significantly, while the DM digestibility showed a strong tendency towards a lower digestibility as the percentage vine husks and pips increased in the diet (Table 3).…”

Section: Resultsmentioning

confidence: 99%

Nutritive value of red vine husks and pips for sheep

2004

SA J. An. Sci.

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The potential of red vine husks and pips as a component of animal feed was investigated. Twenty-five Dohne Merino ram lambs (mean live weight ± s.d. = 41.4 ± 2.3 kg) were used. A completely randomised design was used and the animals were assigned to five diets including 0, 12.5, 25.0, 37.5 and 50% vine husks and pips together with pelleted lucerne hay, respectively. The voluntary intake of feed and water were not negatively influenced by the percentage vine husks and pips included in the diet. The digestibility of the crude protein, neutral detergent fibre and acid detergent fibre decreased significantly, while the dry matter digestibility showed a strong tendency towards a lower digestibility as the percentage vine husks and pips increased in the diet. According to the plasma metabolites, no toxic effects were evident in this study.

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Tannic acid intoxication in sheep and mice

Cited by 71 publications

References 21 publications

Influence of tannic acid application on alfalfa hay: in vitro rumen fermentation, serum metabolites and nitrogen balance in sheep

Influence of tannic acid application on alfalfa hay: in vitro rumen fermentation, serum metabolites and nitrogen balance in sheep

Anaerobic degradation of tannins in <i>Acacia nilotica</i> pods by <i>Enterococcus faecalis</i> in co-culture with ruminal microbiota

Nutritive value of red vine husks and pips for sheep

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