Tannic acid inhibits in vitro iron-dependent free radical formation

Andrade, Roberto G.; Ginani, Janini Selva; Lopes, George K.B.; Dutra, Fernando; Alonso, Antônio; Hermes‐Lima, Marcelo

doi:10.1016/j.biochi.2006.02.006

Cited by 72 publications

(50 citation statements)

References 37 publications

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“…The use of vegetable tannins such as quebracho, mimosa, gall-nut, chestnut and valonia as a biocide in leather soaking process was also studied [18] owing to their antimicrobial and antiseptic properties [19]. Tannic acid, which is a commercially important hydrolysable gallotannin, has also got a great deal of attention as an antimicrobial agent due to its antimicrobial, antimutagenic, anticarcinogenic and antioxidant properties [1, 3,4,10,22,23,31,35,37,41,44]. Tannic acid is present in a variety of fruits and vegetables including tea, cocoa, beans, grapes, strawberry, persimmon, especially the bark of the oak species, sumac and myrobalan [1, 11,40] and also categorized as a 'generally recognized as safe' (GRAS) food additive [1].…”

Section: Introductionmentioning

confidence: 99%

Eco-Friendly Soaking Process Using Tannic Acid as an Alternative Bactericide

Zengin¹,

Çolak²,

Zengin³

et al. 2014

Archives of Environmental Protection

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Eco-friendly leather processes based on the usage of natural products have become a potentially attractive issue for leather industry during the last few decades. Synthetic protective chemicals like bactericides used in most soaking process are known as hazardous substances and cause tannery effl uents with high concentrations of Chemical Oxygen Demand (COD). In the present study, the effect of tannic acid on microorganisms, skin, wool and effl uent were investigated in order to demonstrate the applicability of tannic acid in soaking process instead of commonly used bactericides. The bacterial load (cfu/ml), COD and Nitrogen Content (N) of the soaking effl uents and Total Kjeldahl Nitrogen (TKN) content of skins and wools were investigated. Application of 0.5 and 1 wt% tannic acid concentrations was more effective than commercial bactericide, while comparable results were achieved by 0.1 and 0.3 wt% tannic acid. The application of tannic acid for soaking process resulted in lower COD and N values of effl uents. The results show that tannic acid has the potential to be an alternative, eco-friendly bactericide for leather industry by reducing the pollution of leather soaking process.

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Section: Introductionmentioning

confidence: 99%

Eco-Friendly Soaking Process Using Tannic Acid as an Alternative Bactericide

Zengin¹,

Çolak²,

Zengin³

et al. 2014

Archives of Environmental Protection

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“…By reducing the levels of available iron, TA can diminish the formation of reactive oxygen species via the Fenton reaction, thereby reducing oxidative stress (6,37,38). TA may also scavenge HO radicals through its many phenolic groups that act as efficient nucleophiles (39,40).…”

mentioning

confidence: 99%

Effect of Tannic Acid on the Transcriptome of the Soil Bacterium Pseudomonas protegens Pf-5

Lim

Penesyan

Hassan

et al. 2013

Appl Environ Microbiol

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bTannins are a diverse group of plant-produced, polyphenolic compounds with metal-chelating and antimicrobial properties that are prevalent in many soils. Using transcriptomics, we determined that tannic acid, a form of hydrolysable tannin, broadly affects the expression of genes involved in iron and zinc homeostases, sulfur metabolism, biofilm formation, motility, and secondary metabolite biosynthesis in the soil-and rhizosphere-inhabiting bacterium Pseudomonas protegens Pf-5.

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“…Substâncias tânicas presentes no extrato de P. stipulacea formam um complexo enzimático capaz de provocar danos à parede celular e citoplasmática, inviabilizando a troca de íons essenciais para a sobrevivência microbiana (LOGUERCIO et al, 2005;ANDRADE JR et al, 2006). Desta forma, os taninos de P. stipulacea oportunizam uma alternativa aos antibióticos tradicionais, que devido ao uso abusivo têm favorecido o surgimento de resistência e multirresistência, fato que diiculta o tratamento de infecções causadas por S. aureus, sendo uma fonte para a produção de compostos antimicrobianos.…”

Section: Resultsunclassified

“…De acordo com vários autores, as substâncias tânicas, presentes nos extratos de plantas medicinais, possuem ação sobre vários microrganismos inibindo seu crescimento, o que faz dos vegetais uma excelente fonte de novos compostos biologicamente ativos (JONES et al, 1991;SCALBERT, 1991;COWAN, 1999;LOGUERCIO et al, 2005;MICHELIN et al, 2005;ANDRADE JR et al, 2006;PEREIRA et al, 2009;BEZERRA et al, 2011).…”

Section: Introductionunclassified

Taninos: principal componente do extrato Piptadenia stipulacea (Benth) Ducke inibe o crescimento de cepas clínicas de Staphylococcus aureus de origem bovina

et al. 2016

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ResumoEste estudo avalia a atividade antimicrobiana dos taninos presentes na casca do caule da Piptadenia stipulacea (Benth) sobre cepas de Staphylococcus aureus de origem bovina. A atividade antimicrobiana in vitro do tanino foi avaliada pela determinação da concentração mínima inibitória (CIM). Para determinar a CIM, os taninos foram dissolvidos de forma seriada em água destilada em concentrações variando entre 500 mg/mL e 0,976 mg/mL. Os ensaios foram realizados em triplicata. Os taninos inibiram o crescimento de S. aureus, apresentando valor de CIM de 31,25 mg/mL. Os resultados deste estudo são promissores, pois mostram a importância de avaliar novos compostos de origem natural no combate às infecções causadas por S. aureus. Novos estudos são necessários para conirmar a atividade in vivo e avaliar o mecanismo de ação do tanino isolado da casca do caule da Piptadenia stipulacea. Palavras-chave:

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Tannic acid inhibits in vitro iron-dependent free radical formation

Cited by 72 publications

References 37 publications

Eco-Friendly Soaking Process Using Tannic Acid as an Alternative Bactericide

Eco-Friendly Soaking Process Using Tannic Acid as an Alternative Bactericide

Effect of Tannic Acid on the Transcriptome of the Soil Bacterium Pseudomonas protegens Pf-5

Taninos: principal componente do extrato Piptadenia stipulacea (Benth) Ducke inibe o crescimento de cepas clínicas de Staphylococcus aureus de origem bovina

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