“…the actions of multiple regulators of COPII-mediated transport via its ability to associate with numerous factors including Sar1, Sec24, Sec31, Sec16, TRAPPC3, p125A, members of the TANGO1 cargo receptor family, and, now, TFG (10,14,36,39,(54)(55)(56). Some of these interactions have been shown to be competitive, suggesting that unique associations with Sec23 occur sequentially as transport carriers form, undergo scission from the ER, and tether to ERGIC membranes (14,40).…”