Abstract:Pectus excavatum is the most common type of congenital chest wall abnormality (90%), occurs in an estimated 1 in 300-400 births, with male predominance (male-to-female ratio of 3:1). The exact mechanism involved in this abnormal bone and cartilage overgrowth is not known, and, to date, no known genetic defect is directly responsible for the development of pectus excavatum. Despite the lack of an identifiable genetic marker, the familial occurrence of pectus deformity is reported in 35% of cases. The main aim o… Show more
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