Tamarindus indica seeds improve carbohydrate and lipid metabolism: An in vivo study

Uchenna, Uzukwu Emmanuel; Shori, Amal Bakr; Baba, Ahmad Salihin

doi:10.1016/j.jaim.2017.06.004

Cited by 7 publications

(6 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The oldest traditional medicines have many therapeutic activities including anticancer, antiinflammatory, antiallergic, antidiabetes, and immunosuppressant. The specific phenolic compounds detected in these plant extracts agree with the compounds identified in literature, such as catechin and cinnamic acid (Guneidy et al, 2017;Uchenna et al, 2018).…”

Section: Discussionsupporting

confidence: 87%

Evaluation of Phenolic Content Diversity along with Antioxidant/Pro-Oxidant, Glutathione Transferase Inhibition, and Cytotoxic Potential of Selected Commonly Used Plants

Guneidy

Zaki

Gad

et al. 2022

Prev. Nutr. Food Sci.

View full text Add to dashboard Cite

The function of antioxidant polyphenols has been demonstrated for their ability to protect against a variety of diseases. However, some antioxidants have been shown to be pro-oxidant. Some of the important antioxidant enzymes are glutathione transferases (GST), which are involved in maintaining redox homeostasis. GST class Pi (GSTP1-1) hyperactivation is a feature that is found in cancer. This work aims to demonstrate the relationship between the phytochemicals of 18 plants and their ability to act as antioxidant/pro-oxidant agents, as well as their effects on the activity of GSTP1-1 and their cellular toxicity. Tamarindus indica, Cinnamomum verum, and Alpinia galanga extracts had high phytochemical contents, moderate heavy metal levels, and antioxidant/pro-oxidant activities. Among the main plant components identified using high-performance liquid chromatography, only chlorogenic acid, catechin, and quercetin can function as antioxidants and pro-oxidants. Hibiscus sabdariffa, C. verum, A. galanga, T. indica, Gossypium arboreum, and Punica granatum were among the plant extracts examined that inhibited the activity of the purified recombinant GSTP1-1, with the inhibition constant values ranging from 0.48 to 1.67 mg of gallic acid equivalent/g. The level of cytotoxicity was also studied to determine the effects of these extracts on human Caucasian breast cancer. The findings revealed that plants with high phenol content had an antioxidant/pro-oxidant capacity as well as inhibition of the activity of GST. However, the cytotoxic effect was not associated with all of the extracts, which indicates that polyphenols interact with other components that may influence their observed behavior.

show abstract

Section: Discussionsupporting

confidence: 87%

Evaluation of Phenolic Content Diversity along with Antioxidant/Pro-Oxidant, Glutathione Transferase Inhibition, and Cytotoxic Potential of Selected Commonly Used Plants

Guneidy

Zaki

Gad

et al. 2022

Prev. Nutr. Food Sci.

View full text Add to dashboard Cite

show abstract

“…A literatura apresenta diversos benefícios nos parâmetros de triacilglicerol, colesterol total, LDL-c, HDL-c e composição corporal com o uso do tamarindo em modelos animais (UCHENNA et al,2017;AZMAN et al, 2012;JINDAL et al, 2011).…”

Section: Resultsunclassified

Segurança No Trabalho: Acidentes E Uso De Equipamentos De Proteção Individual Em Restaurantes Comerciais

Moreira¹,

Souza²,

Sampaio³

et al. 2018

Avanços E Desafios Da Nutrição No Brasil

View full text Add to dashboard Cite

show abstract

“…Aqueous extract of the tamarind seeds had potent antidiabetic activity that reduced blood sugar levels in streptozotocin (STZ) induced diabetic male rat 36 . The tamarind seeds are included in a lower percentage in diet (4% and 8%) and were found to reduce the blood glucose level and serum cholesterol in rats 37 . Administration of seed pectin also reduced blood glucose concentration by 30% after 24 hours 38 .…”

Section: Hypoglycemic Activitymentioning

confidence: 99%

A Scientific Evidence-based Review of Tamarind usage in Indian Folklore Medicine

Raja

Poonguzhali²,

Rao³

et al. 2022

JNR

View full text Add to dashboard Cite

Currently, the paradigm shift of folklore medicine is obvious among the public and researchers. Study based on traditional medicine around the world has become prominent with the addition of pharmacological studies to scientifically prove the effectiveness of the concerned medicine. Tamarind (Tamarindus indica L. of family Fabaceae) alone or with a combination of other herbs has been proved to be effective for treating many ailments such as arthritis, dysuria, dental diseases, ulcer, sexual dysfunction, etc. It also exhibits pharmacological actions such as antimicrobial, anti-dysentery, anti-coagulant, hepatoprotective, anti-asthmatic, and anti-diabetic. The pharmacological effect of the fruit or the pulp, leaves, flowers, kernel, and inner bark has been studied. Furthermore, different species of tamarind have also been studied. Numerous studies such as chemical, analytical and biological were conducted to confirm the same. The clinical studies of tamarind match with folklore practices with respect to pharmacological actions, still some are yet to be explored. This study focuses on reviewing the chemical composition, pharmacological effects, and nutritional effects of tamarind. Hence it can be concluded that the folklore practice and modern medicinal practice interact with each other. Thus, the folklore practices without being neglected can be extended for the support of scientific evidence through detailed researches.

show abstract

Tamarindus indica seeds improve carbohydrate and lipid metabolism: An in vivo study

Abstract: Tamarind seeds can lower blood glucose and serum cholesterol and enhance storage of glycogen in rats.

Cited by 7 publications

References 44 publications

Evaluation of Phenolic Content Diversity along with Antioxidant/Pro-Oxidant, Glutathione Transferase Inhibition, and Cytotoxic Potential of Selected Commonly Used Plants

Evaluation of Phenolic Content Diversity along with Antioxidant/Pro-Oxidant, Glutathione Transferase Inhibition, and Cytotoxic Potential of Selected Commonly Used Plants

Segurança No Trabalho: Acidentes E Uso De Equipamentos De Proteção Individual Em Restaurantes Comerciais

A Scientific Evidence-based Review of Tamarind usage in Indian Folklore Medicine

Contact Info

Product

Resources

About