“…Findings similar to our study are also seen in Berardinelli Seip syndrome[13] and Alstrom's syndrome,[14] where DM is one of the features. Here enamel hypoplasia and occurrence of talon's cusp are reported, with etiology probably due to this endocrine disturbance, DM.…”
Section: Discussionsupporting
confidence: 91%
“…Here enamel hypoplasia and occurrence of talon's cusp are reported, with etiology probably due to this endocrine disturbance, DM. [13] The proposed hypothesis for the formation of Talon's cusp in this study are “hyperproductivity of the anterior ends of dental lamina, disturbances during morphodifferentiation, such as altered endocrine function, which may affect the shape and size of a tooth without impairing the functions of ameloblasts or odontoblasts, and malinteraction between ectoderm and mesoderm at the time of complex odontogenesis process on the epithelial buddings of the premaxillary region.”[13]…”
Introduction:Type 1 diabetes mellitus (DM) is an endocrine disorder that occurs commonly in an age group, where the development of primary and permanent dentition takes place. As altered endocrine functions may affect the shape and size of teeth leading to dental anomalies, this study was conducted to look for the occurrence of any dental anomalies in type I DM patients.Materials and Methods:A diabetic camp was conducted at Alur Chandrashekharappa Memorial Hospital, Davangere, where 30 diabetic patients were examined and the impressions of their maxillary and mandibular arches were recorded. Age and sex matched controls were selected randomly, and similar recordings were done.Results:Type I diabetic patients showed statistically significant (P < 0.001) morphological alterations of total number of cusps, including presence of 6th cusp in mandibular molars and extra cusps in mandibular premolars. Other alterations such as microdontia, flower shaped mandibular molars, prominent cusp of carabelli, and oblique ridge in maxillary molars were also noted. Severe attrition was found in 11 (36.6%) of the diabetic patients, whereas the control group showed attrition only in 2 (6.8%) patients.Conclusion:Remarkable morphological alterations do occur in the dentition of type I DM patients.
“…Findings similar to our study are also seen in Berardinelli Seip syndrome[13] and Alstrom's syndrome,[14] where DM is one of the features. Here enamel hypoplasia and occurrence of talon's cusp are reported, with etiology probably due to this endocrine disturbance, DM.…”
Section: Discussionsupporting
confidence: 91%
“…Here enamel hypoplasia and occurrence of talon's cusp are reported, with etiology probably due to this endocrine disturbance, DM. [13] The proposed hypothesis for the formation of Talon's cusp in this study are “hyperproductivity of the anterior ends of dental lamina, disturbances during morphodifferentiation, such as altered endocrine function, which may affect the shape and size of a tooth without impairing the functions of ameloblasts or odontoblasts, and malinteraction between ectoderm and mesoderm at the time of complex odontogenesis process on the epithelial buddings of the premaxillary region.”[13]…”
Introduction:Type 1 diabetes mellitus (DM) is an endocrine disorder that occurs commonly in an age group, where the development of primary and permanent dentition takes place. As altered endocrine functions may affect the shape and size of teeth leading to dental anomalies, this study was conducted to look for the occurrence of any dental anomalies in type I DM patients.Materials and Methods:A diabetic camp was conducted at Alur Chandrashekharappa Memorial Hospital, Davangere, where 30 diabetic patients were examined and the impressions of their maxillary and mandibular arches were recorded. Age and sex matched controls were selected randomly, and similar recordings were done.Results:Type I diabetic patients showed statistically significant (P < 0.001) morphological alterations of total number of cusps, including presence of 6th cusp in mandibular molars and extra cusps in mandibular premolars. Other alterations such as microdontia, flower shaped mandibular molars, prominent cusp of carabelli, and oblique ridge in maxillary molars were also noted. Severe attrition was found in 11 (36.6%) of the diabetic patients, whereas the control group showed attrition only in 2 (6.8%) patients.Conclusion:Remarkable morphological alterations do occur in the dentition of type I DM patients.
“…Talon cusp is reported to occur with genetic syndromes including Alagille's Syndrome (Chatterjee & Mason, 2007), Berardinelli-Seip Syndrome (Solanki et al, 2008), Ellis-Van Creveld Syndrome (Hattab et al, 1998), incontinentia pigmenti achromians (Tsutsumi & Oguchi, 1991), Mohr Syndrome (Goldstein & Medina, 1974), Rubinstein-Taybi Syndrome (RTS, Sakurai et al, 1966;Gardner & Girgis, 1979;Kinirons, 1983;Baker, 1987;Hennekam & van Doorne, 1990), Sotos Syndrome (Gomes-Silve et al, 2006) and Sturge-Weber Syndrome (Chen & Chen, 1986). The majority of these cases are isolated incidences, and it is premature to conclude that talon cusp is associated with these conditions (Tsutsumi & Oguchi, 1991).…”
Section: Clinical Associations Of Talon Cuspsmentioning
The specimen reported here presents a rare form of dental variant-a permanent, mandibular labial canine talon cusp. This anomaly has not previously been reported in the clinical or archaeological literatures and is currently unique. The affected individual is an adult male from the Early Holocene cemetery of Gobero located in the Sahara Desert in the Republic of Niger. The age of this site (ca. 9500 bp) makes this the first archaeological case of labial talon cusp from Africa and the oldest reported talon cusp of any kind (lingual or labial, maxillary or mandibular, incisor or canine) in the world. Previous case studies, population frequency data, sexual dimorphism patterns and distribution within the dentition are discussed for labial talon cusp. The morphological aetiology of talon cusps is reviewed with respect to this specimen.
We report a 2.5 year old male, first in order of birth of first cousin consanguineous parents with the typical features of Berardinelli-Seip congenital lipodystrophy 2 (BSCL2) since birth with moderate mental retardation. He had generalized lipodystrophy with various dermatologic and systemic manifestations. The patient looked older than his age with the loss of buccal pad of fat, hypertrichosis mainly on the back and lower limbs, thick scalp hair, mild prognathism, large hands and feet with prominent joints and muscular hypertrophy. Acanthosis nigricans was evident over the neck and both axillae inspite of the normal level of sugar and insulin. The abdomen was markedly prominent with mild hepatosplenomegaly and enlarged external genitals. Echo-cardiography demonstrated cardiac hypertrophy. Triglyceride level was high with reduced high density lipoproteins (HDL).Ó 2014 Production and hosting by Elsevier B.V. on behalf of Ain Shams University.
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