Talaromyces marneffei laboratory cross reactivity with Histoplasma and Blastomyces urinary antigen

Vega, Pool Tobar; Erramilli, Shruti; Lee, Eugene

doi:10.1016/j.ijid.2019.06.018

Cited by 4 publications

(2 citation statements)

References 12 publications

(7 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A combination of clinical suspicion and antigenic testing usually guides therapy. However, histology and cultures are the gold standard and may be required, given that Blastomyces antigenic testing has been shown to have cross reactivity with other fungal infections [ 1 , 5 ]. Pulmonary blastomycosis has non-specific symptoms (fever, weight loss, shortness of breath, cough) and can present in an acute or chronic manner with different degrees of severity.…”

Section: Discussionmentioning

confidence: 99%

Unusual presentation of pulmonary blastomycosis complicated by amphotericin-induced refractory electrolyte abnormalities

Tobar

Sánchez-Nadales

Caldeira

et al. 2020

Oxford Medical Case Reports

View full text Add to dashboard Cite

Blastomyces dermatitidis is an endemic mold infection commonly seen in the midwestern of the USA and rarely affects pregnant women. The most common presentation is a pulmonary infection with variable degrees of severity. Of note, the clinical and radiographic findings of pulmonary blastomycosis can be mistaken for other pulmonary pathologies, thus earning the title of ‘the great pretender’. The treatment of choice of infected pregnant patients is amphotericin B, which is known to produce electrolyte imbalances. However, it infrequently causes severe, prolonged and profound hypokalemia and hypomagnesemia. We present the case of a 27-year-old pregnant patient with pulmonary blastomycosis presenting with a lung mass suspicious of malignancy and treated with amphotericin B with subsequent prolonged refractory hypokalemia and hypomagnesemia. Keywords pulmonary blastomycosis pregnancy biopsy computed tomography angiography liposomal amphotericin B

show abstract

Section: Discussionmentioning

confidence: 99%

Unusual presentation of pulmonary blastomycosis complicated by amphotericin-induced refractory electrolyte abnormalities

Tobar

Sánchez-Nadales

Caldeira

et al. 2020

Oxford Medical Case Reports

View full text Add to dashboard Cite

show abstract

“…As occurs with other endemic mycoses, antigen detection is particularly useful to diagnose talaromycosis in PLWHA that fail to produce specific T. marneffei antibodies. Special attention must be given to possible serologic cross-reactions that may occur when patients with talaromycosis are tested for Histoplasma , Blastomyces , or Aspergillus antigens [ 129 , 182 ].…”

Section: Talaromycosismentioning

confidence: 99%

Immunologic Diagnosis of Endemic Mycoses

Almeida‐Paes

Bernardes-Engemann

Motta

et al. 2022

JoF

View full text Add to dashboard Cite

The endemic mycoses blastomycosis, coccidioidomycosis, histoplasmosis, paracoccidioidomycosis, cryptococcosis, sporotrichosis, talaromycosis, adiaspiromycosis, and emergomycosis are mostly caused by geographically limited thermally dimorphic fungi (except for cryptococcosis), and their diagnoses can be challenging. Usual laboratory methods involved in endemic mycoses diagnosis include microscopic examination and culture of biological samples; however, serologic, histopathologic, and molecular techniques have been implemented in the last few years for the diagnosis of these mycoses since the recovery and identification of their etiologic agents is time-consuming and lacks in sensitivity. In this review, we focus on the immunologic diagnostic methods related to antibody and antigen detection since their evidence is presumptive diagnosis, and in some mycoses, such as cryptococcosis, it is definitive diagnosis.

show abstract

Talaromyces stipitatus, a novel agent causing superficial mycosis in a diabetic patient from North India

Sharma

Nonzom

2022

Microbes and Infection

View full text Add to dashboard Cite

Talaromyces marneffei laboratory cross reactivity with Histoplasma and Blastomyces urinary antigen

Cited by 4 publications

References 12 publications

Unusual presentation of pulmonary blastomycosis complicated by amphotericin-induced refractory electrolyte abnormalities

Unusual presentation of pulmonary blastomycosis complicated by amphotericin-induced refractory electrolyte abnormalities

Immunologic Diagnosis of Endemic Mycoses

Talaromyces stipitatus, a novel agent causing superficial mycosis in a diabetic patient from North India

Contact Info

Product

Resources

About