Takotsubo syndrome and dialysis: an uncommon association?

Abstract

This review was performed to investigate the association between treatment with dialysis and Takotsubo syndrome in patients with end-stage renal disease. We systematically explored the PubMed database using the search terms “Takotsubo cardiomyopathy” and/or “stress-induced cardiomyopathy” and/or “Takotsubo syndrome” in combination with “dialysis” and “uremia.” Of 3630 articles found, 8 articles reporting 10 cases were selected for analysis. Most patients were women, and their age ranged from 51 to 84 years. Diabetes mellitus and hypertension were diagnosed in 40% of patients, and glomerular disease was diagnosed in 30%. One only patient was treated with peritoneal dialysis; all others were treated with hemodialysis. The outcome was unfavorable in only one patient. An association between Takotsubo syndrome and dialysis is uncommon, but not negligible, and comorbidities play a major role in determining the clinical outcome.

Takotsubo Syndrome during Haemodialysis

“…In this case report, we present the 11 th case of a patient on hemodialysis, who presented with TS and complicated with cardiogenic shock, which is a very rare complication of the syndrome and restored in few days. [6]…”

Is Takotsubo Syndrome Still a Benign Disease? Complications (and Gender) Make the Difference

“…4,5 Growing knowledge is accumulating on the relationship between TTS and a series of pathologic conditions, such as coronary artery, neurologic, psychiatric, renal, and infectious diseases. [5][6][7][8] In this issue of Angiology, El-Battrawy et al 9 evaluated inhospital, and long-term incidence of thromboembolic events of 138 consecutive patients with TTS, compared with 138 sexand age-matched patients with acute coronary syndrome (ACS) in a single center in Germany. The incidence of thromboembolic events in TTS was 2-fold higher than for ACS (21% vs 9%; P < .01) over a mean follow-up of 5 years.…”

“…Growing knowledge is accumulating on the relationship between TTS and a series of pathologic conditions, such as coronary artery, neurologic, psychiatric, renal, and infectious diseases. 5 –8…”