Tako-Tsubo cardiomyopathy with coronary artery stenosis: A case-series challenging the original definition

Gaibazzi, Nicola; Ugo, Fabrizio; Vignali, Luigi; Zoni, Antonello; Reverberi, Claudio; Gherli, Tiziano

doi:10.1016/j.ijcard.2007.12.037

Cited by 59 publications

(36 citation statements)

References 13 publications

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“…There's no reason to believe that an individual with established stable coronary artery disease would not also develop takotsubo cardiomyopathy. A previously published case series documented a 10% incidence of coronary artery disease in 97 Japanese patients diagnosed with takotsubo cardiomyopathy [12] , while another study showed at least 50% stenosis of one epicardial coronary artery in seven patients that presented with takotsubo cardiomyopathy [13] . Although the Mayo Clinic has formulated a set of diagnostic criteria to recognize stress cardiomyopathy, the approach to patients present with ST elevation will remain the same [14] .…”

Section: Discussionmentioning

confidence: 95%

Paraneoplastic pemphigus vulgaris resulted in takotsubo cardiomyopathy: a case report

Elsheshtawy

Abdel-Shafy

Siegel

2015

CRIM

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Paraneoplastic pemphigus (PNP) is an autoimmune bullous disease characterized by intractable stomatitis and is associated with different malignancies. Mortality, if associated with the disease, is usually attributed to skin lesion infection or respiratory failure. Reversible cardiomyopathy, also known as takotsubo cardiomyopathy, is a reversible left ventricular dysfunction that is always triggered by intense physical or emotional stressors. To our knowledge, this is the first case to report mortality in paraneoplastic pemphigus vulgaris from takotsubo cardiomyopathy. This case illustrates the psychosocial impact of serious skin diseases that can affect mortality even when there is a favorable prognosis.

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Section: Discussionmentioning

confidence: 95%

Paraneoplastic pemphigus vulgaris resulted in takotsubo cardiomyopathy: a case report

Elsheshtawy

Abdel-Shafy

Siegel

2015

CRIM

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“…There is an adequate amount of evidence in the literature indicating that obstructive coronary artery disease and TS may coexist [13,14,15]. Recently, TS triggered by coronary artery spasm and acute myocardial infarction has been reported [16,17,18].…”

Section: Discussionmentioning

confidence: 99%

Bromocriptine-Induced Coronary Spasm Caused Acute Coronary Syndrome, Which Triggered Its Own Clinical Twin – Takotsubo Syndrome

Y‐Hassan

Jernberg²

2011

Cardiology

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Bromocriptine-induced coronary spasm (BICS) causing myocardial infarction has been reported. Association between BICS and Takotsubo syndrome (TS) has not been described. We report on a 37-year-old woman presenting with a clinical picture of acute coronary syndrome 1 day after initiation of treatment with bromocriptine for ablactation 3 weeks after a full-term spontaneous vaginal delivery. Coronary angiography showed diffuse narrowing of a large diagonal branch. Left ventriculography showed widespread hypokinesia extending beyond the diagonal branch supply region. There was a slight elevation of myocardial infarction biomarkers that was disproportional to the degree of left ventricular dysfunction. Follow-up coronary angiography, intravascular ultrasound and left ventriculography showed normal coronary arteries including the diagonal branch and complete normalization of the left ventricular function. Cardiac magnetic resonance examination showed no signs of late myocardial gadolinium enhancement. The clinical picture and course of the disease was consistent with TS. Consequently, we describe for the first time a case of TS triggered by myocardial ischemia caused by BICS. Furthermore, our case and sufficient supporting data from the literature demonstrate that acute coronary syndrome is an important and frequent but up till now missed trigger factor for TS.

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“…41 Another series described 7 patients with TC had concomitant coronary artery disease with at least 1 epicardial coronary artery stenosis of 50% or more. 42 Thus, the presence of coronary artery disease does not exclude the diagnosis of TC. Left ventriculography performed at the time of coronary angiography, in a patient with suspected ACS but without obstructive coronary artery disease, is useful to investigate whether the patient has TC.…”

Section: Coronary Angiography and Left Ventriculographymentioning

confidence: 99%

Clinical Characteristics and Outcomes of Takotsubo Cardiomyopathy

Looi¹,

Kerr²

2016

ICFJ

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Takotsubo cardiomyopathy (TC) is a transient, reversible form of cardiomyopathy which predominantly affects post-menopausal women and is an important differential diagnosis of acute coronary syndrome. It is characterised by normal (or near-normal) coronary arteries, regional wall motion abnormalities that extend beyond a single coronary vascular bed, and often proceeded by a stressful event. The pathophysiologic mechanism is complex and remains to be elucidated. There is increasing awareness among physicians about TC and hence, more cases are being reported. The diagnosis of TC has important clinical implications in the management at presentation and afterward. In this review, we discuss the demographics, clinical features, prognosis and management of this cardiomyopathy.

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Tako-Tsubo cardiomyopathy with coronary artery stenosis: A case-series challenging the original definition

Cited by 59 publications

References 13 publications

Paraneoplastic pemphigus vulgaris resulted in takotsubo cardiomyopathy: a case report

Paraneoplastic pemphigus vulgaris resulted in takotsubo cardiomyopathy: a case report

Bromocriptine-Induced Coronary Spasm Caused Acute Coronary Syndrome, Which Triggered Its Own Clinical Twin – Takotsubo Syndrome

Clinical Characteristics and Outcomes of Takotsubo Cardiomyopathy

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