Tako-Tsubo cardiomyopathy after influenza vaccination

Takotsubo Syndrome During the COVID-19 Pandemic: State-of-the-Art Review

“…TTS has been previously reported in infectious diseases, mainly in bacterial sepsis, and rarely in the setting of viral infections (47,48). The influenza virus is one of the most recognized viruses to cause TTS during the acute infection or following vaccination (49)(50)(51)(52)(53)(54)(55)(56). However, the incidence of TTS in the setting of influenza or other viral infections is not known since no studies have been dedicated to investigate the echocardiographic findings in the affected patients.…”

Drug-Induced Takotsubo Cardiomyopathy

“…87 Phentermine is an amphetamine derivative used as an appetite suppressant, which is thought to be a sympathomimetic amines that stimulate the release of norepinephrine and dopamine from the storage sites in the presynaptic nerve terminals. 119 Other catecholamine-related causes included indirect adrenergic effects, including parasympathetic block (2 cases), 117,122 sudden withdrawal of b-blockers (3 cases), 76,77 anaphylactic reactions (5 cases), [81][82][83][84]118 withdrawal of opioids (5 cases), 69,70,75,78,79 or alcohol (2 cases). 71,125 Opioid withdrawal is known to cause hyperadrenergic state that leads to catecholamine surge and increased b-receptor sensitivity and subsequently myocardial stunning.…”

“…137 Ibuprofen was called a cause of TCM, while the patient described in the case suffered cardiac arrest and underwent extensive cardiopulmonary resuscitation with massive doses of epinephrine. 113 Only handful of cases remain unexplained: androgenic steroids in the setting of hypothyroidism, 114 interleukin 2, 115 entacapone, 116 influenza vaccine, 118 dipyridamole, 88 and convulsions and takotsubo in a 97-year-old patient after levofloxacin and a nonsteroidal anti-inflammatory drug loxoprofen. 123…”

Takotsubo cardiomyopathy triggered by influenza A and complicated with cardiac arrest, a case report

“…1,2 The pathophysiology of Takotsubo cardiomyopathy is still unclear, although several mechanisms have been proposed1; moreover, Takotsubo has been related to pulmonary infection 3 and influenza virus vaccination. 4 Patients with Takotsubo cardiomyopathy have a favorable short-and long-term prognosis compared with those with acute myocardial infarction, secondary to the complete recovery of cardiac function. Nevertheless, cardiac arrest is a rare, but extremely lethal, complication.…”