Takatsuki disease.

民子, 朔; 修平, 今山; 治邦, 占部; 靖生, 林

doi:10.2336/nishinihonhifu.47.224

Cited by 2 publications

(2 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The relative low reported incidence of cutaneous angiomas in the Crow-Fukase syndrome might be attributable to either ignorance or mistaking the cutaneous angiomas as cherry angiomas or pyogenic granulomas. However, the cutaneous angioma in Crow-Fukase syndrome shows a histopathology that differs from cherry angioma and pyogenic granuloma (5,7,8,11,12). The presence ofWeibel-Palade granules and FVIII-RAG in the plump cells supports that they are endothelial cells.…”

Section: Discussionmentioning

confidence: 95%

See 1 more Smart Citation

Cutaneous Angioma in Crow‐Fukase Syndrome: The Nature of Globules within the Endothelial Cells

Jitsukawa

Hayashi

Sato

et al. 1988

The Journal of Dermatology

View full text Add to dashboard Cite

To clarify the nature of the intracytoplasmic globules seen in the endothelial cells of the cutaneous angiomas of the Crow‐Fukase syndrome, we performed light and electron microscopic as well as immunohistochemical studies. The proliferating plump endothelial cells of the angioma located in the mid‐dermal portion contained numerous globules. IgG, A, M, and kappa and lambda light chain globulins were present in the endothelial cells containing these globules. Electron microscopy revealed osmiophilic fine fibrillar structures and amorphous substance in the globules. Thiéry staining for detection of vicinal‐glycol radicals of carbohydrate demonstrated the deposition of fine silver particles as a reaction product. We consider that the intracytoplasmic globules are phagolysosomes containing glycoprotein.

show abstract

Section: Discussionmentioning

confidence: 95%

“…Apparently, the inci-dence ofthis syndrome is higher inJapan than in any other country. The skin changes seen in Crow-Fukase syndrome include hyperpigmentation, hypertrichosis, hardening of the skin, hyperhidrosis, edema, white nails, clubbing of the fingers, and cutaneous angiomas (3)(4)(5)(6)(7)(8).…”

Section: Introductionmentioning

confidence: 99%