Taiwan’s National Health Insurance Research Database: administrative health care database as study object in bibliometrics

Chen, Yu‐Chun; Yeh, Hsiao-Yun; Wu, Jau‐Ching; Haschler, Ingo; Chen, Tzeng Ji; Wetter, Thomas C.

doi:10.1007/s11192-010-0289-2

Cited by 257 publications

(187 citation statements)

References 17 publications

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“…The study was approved by the institutional review board of the Taipei Veterans General Hospital, Taiwan, because the NHIRD contains anonymous secondary data released to the public for research purposes. 2 …”

Section: Databasementioning

confidence: 99%

Epidemiology of cervical spondylotic myelopathy and its risk of causing spinal cord injury: a national cohort study

Yen

et al. 2013

FOC

Self Cite

169

115

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Object This study aimed to determine the age- and sex-specific incidence of cervical spondylotic myelopathy (CSM) and its associated risk of causing subsequent spinal cord injury (SCI). Methods Using the National Health Insurance Research Database (NHIRD), a 12-year nationwide database in Taiwan, this retrospective cohort study analyzed the incidence of hospitalization caused by CSM. All patients diagnosed with and admitted for CSM were identified during the study period. The CSM patients were divided into 2 groups, a control group and an operated group. An incidence density method was used to estimate age- and sex-specific incidence rates of CSM. The Kaplan-Meier method and Cox regression analyses were performed to compare the risk of SCI between the 2 groups. Results From 1998 to 2009, covering 349.5 million person-years, 14,140 patients were hospitalized for CSM. The overall incidence of CSM-related hospitalization was 4.04 per 100,000 person-years. Specifically, males and older persons had a higher incidence rate of CSM. During the follow-up of these patients for 13,461 person-years, a total of 166 patients were diagnosed with SCI. The incidence of SCI was higher in the control group than the operated group (13.9 vs 9.4 per 1000 person-years, respectively). During the follow-up, SCI was more likely to occur in CSM patients who were treated conservatively (crude HR 1.48, p = 0.023; adjusted HR 1.57, p = 0.011) than in those who underwent surgery for CSM. Conclusions In a national cohort of eastern Asia, the incidence of CSM-caused hospitalization was 4.04 per 100,000 person-years, with higher incidences observed in older and male patients. Subsequent SCI was more likely to develop in patients who received nonoperative management than in those who underwent surgery. Therefore, patients with CSM managed without surgery should be cautioned about SCI. However, further investigations are still required to clarify the risks and complications associated with surgery for CSM.

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Section: Databasementioning

confidence: 99%

Epidemiology of cervical spondylotic myelopathy and its risk of causing spinal cord injury: a national cohort study

Yen

et al. 2013

FOC

Self Cite

169

115

View full text Add to dashboard Cite

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“…The completeness and accuracy of the claims data of NHI research database were appropriately monitored and maintained by Taiwan's NHI Bureau, and more than 300 studies based on these data have been published in peer-reviewed journals. 19,20 The LHID 2000 consists of de-identified secondary data released to the public for research purposes. After consulting the director of the Institutional Review Board of Taipei Medical University, this study was exempted from full review.…”

Section: Databasementioning

confidence: 99%

Patients With Traumatic Brain Injury

Chen

Kang

Lin

2011

Stroke

109

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Background and Purpose-Previous studies have identified an array of morbidities following traumatic brain injury (TBI), including certain neurological disorders. However, no direct evidence has been reported on the link between TBI and stroke. This population-based study was designed to estimate the risk of stroke during a period of 5 years following a TBI, compared with individuals who did not suffer TBI during the same period. Methods-Data

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“…The claims data are generally accurate; to date, more than 300 studies based on these data have been published in peer-reviewed journals. 12,13 Because we used deidentified secondary data released to the public for research purposes, our study was exempt from full review by the Institutional Review Board after consultation with the Director of Taipei Medical University Institutional Review Board.…”

Section: Data Sourcementioning

confidence: 99%

Risk of herpes zoster among patients with chronic obstructive pulmonary disease: a population-based study

Yang¹,

Chen²,

Wang³

et al. 2011

Canadian Medical Association Journal

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H erpes zoster is caused by a reactivation of latent varicella-zoster virus residing in sensory ganglia after an earlier episode of varicella.1 Herpes zoster is characterized by a painful vesicular dermatomal rash. It is commonly complicated with chronic pain (postherpetic neuralgia), resulting in reduced quality of life and functional disability to a degree comparable to that experienced by patients with congestive heart failure, diabetes mellitus and major depression. 1,2Patients with herpes zoster experience more substantial role limitations resulting from emotional and physical problems than do patients with congestive heart failure or diabetes.3 Pain scores for postherpetic neuralgia have been shown to be as high as those for chronic pain from osteoarthritis and rheumatoid arthritis.3 Although aging is the most well-known risk factor for herpes zoster, people with diseases associated with impaired immunity, such as malignancy, HIV infection, diabetes and rheumatic diseases, are also at higher risk for herpes zoster. 4,5Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow limitation that is associated with an abnormal inflammatory response by the small airways and alveoli to inhaled particles and pollutants.6 Disruption of local defence systems (e.g., damage to the innate immune system, impaired mucociliary clearance) predispose patients with COPD to respiratory tract infections. Each infection can cause exacerbation of COPD and further deterioration of lung function, which in turn increase predisposition to infection. 7,8 There is increasing evidence that COPD is an autoimmune disease, with chronic systemic inflammation involving more than just the airways and lungs.6 Given that various immune-mediated diseases (e.g., rheumatoid arthritis, inflammatory bowel disease) have been reported to be associated with an increased risk of herpes zoster, 4,9,10 it is reasonable to hypothesize that the immune dysregulation found in COPD may put patients at higher risk of developing herpes zoster. In addition, inhaled or systemic corticosteroids used for management of Research CMAJ Background: Systemic inflammation and dysregulated immune function in chronic obstructive pulmonary disease (COPD) is hypothesized to predispose patients to development of herpes zoster. However, the risk of herpes zoster among patients with COPD is undocumented. We therefore aimed to investigate the risk of herpes zoster among patients with COPD. Risk of herpes zoster among patients with chronic obstructive pulmonary disease: a population-based study Methods:We conducted a cohort study using data from the Taiwan Longitudinal Health Insurance Database. We performed Cox regressions to compare the hazard ratio (HR) of herpes zoster in the COPD cohort and in an age-and sex-matched comparison cohort. We divided the patients with COPD into three groups according to use of steroid medications and performed a further analysis to examine the risk of herpes zoster. Results:The study included 8486 patients with COPD and 3...

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Taiwan’s National Health Insurance Research Database: administrative health care database as study object in bibliometrics

Abstract: The trend to use administrative health care databases as research material is increasing but not well explored.

Cited by 257 publications

References 17 publications

Epidemiology of cervical spondylotic myelopathy and its risk of causing spinal cord injury: a national cohort study

Epidemiology of cervical spondylotic myelopathy and its risk of causing spinal cord injury: a national cohort study

Patients With Traumatic Brain Injury

Risk of herpes zoster among patients with chronic obstructive pulmonary disease: a population-based study

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