Tailoring silk fibroin hydrophilicity and physicochemical properties using sugar alcohols for medical device coatings
Supranee Kaewpirom,
Sarayoot Piboonnithikasem,
Pongsathorn Sroisroemsap
et al.
Abstract:This study explores the modification of silk fibroin films for hydrophilic coating applications using various sugar alcohols. Films, prepared via solvent casting, incorporated glycerol, sorbitol, and maltitol, revealing distinctive transparency and UV absorption characteristics based on sugar alcohol chemical structures. X-ray diffraction confirmed a silk I to silk II transition influenced by sugar alcohols. Glycerol proved most effective in enhancing the β-sheet structure. The study also elucidated a conforma… Show more
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