Tailoring Phage Nanosomes for Enhanced Theranostic Properties of Near Infrared Dyes
Sri Amruthaa Sankaranarayanan,
Dokkari Nagalaxmi Yadav,
Saanya Yadav
et al.
Abstract:Near-infrared (NIR) phototherapies offer noninvasive, cost-effective solutions for treating tumors and microbial infections. However, organic NIR dyes commonly used suffer from solubility and stability issues requiring frequent dosing. We address this challenge by exploring the bacteriophage-mediated enhancement of NIR dye properties. Upon encapsulation within phage nanosomes, IR780 and Indocyanine green (ICG), with similar optical properties but distinct water solubility and exhibit enhanced UV−vis absorbanc… Show more
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