2017
DOI: 10.1186/s13054-017-1906-8
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Tailoring nutrition therapy to illness and recovery

Abstract: Without doubt, in medicine as in life, one size does not fit all. We do not administer the same drug or dose to every patient at all times, so why then would we live under the illusion that we should give the same nutrition at all times in the continuum of critical illness? We have long lived under the assumption that critical illness and trauma lead to a consistent early increase in metabolic/caloric need, the so-called “hypermetabolism” of critical illness. What if this is incorrect? Recent data indicate tha… Show more

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Cited by 77 publications
(89 citation statements)
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References 44 publications
(67 reference statements)
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“…If we underfeed in the first week, do we need to overcome the caloric debt? Will there be deleterious effects to patients? There is clinical evidence to suggest targeting caloric debt as an endpoint for nutrition delivery as an effective strategy …”
Section: Studies Suggesting Equivalency Of Feeding Strategiesmentioning
confidence: 99%
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“…If we underfeed in the first week, do we need to overcome the caloric debt? Will there be deleterious effects to patients? There is clinical evidence to suggest targeting caloric debt as an endpoint for nutrition delivery as an effective strategy …”
Section: Studies Suggesting Equivalency Of Feeding Strategiesmentioning
confidence: 99%
“…Will there be deleterious effects to patients? 10 There is clinical evidence to suggest targeting caloric debt as an endpoint for nutrition delivery as an effective strategy. 11 The recent NUTRIREA-2 study points to a potential signal of harm from full feeding, in particular because of gastrointestinal complications, particularly ischemia.…”
Section: Studies Suggesting Equivalency Of Feeding Strategiesmentioning
confidence: 99%
“…However, trial findings and guideline recommendations continue to be conflicting, making the translation of evidence into practice challenging. Further, it is becoming evident that the stage of critical illness and individual factors such as body composition may be important when considering how individuals might respond to nutrition interventions [3,4]. This narrative review aims to provide a summary and interpretation of the adult critical care nutrition literature, with a particular focus on continuing practice gaps and areas with new data, to help clinicians make practical, yet evidencebased decisions regarding nutrition management during critical illness.…”
Section: Introductionmentioning
confidence: 99%
“…The metabolic response to critical illness and the role of nutrition therapy It is recognised that 'one-size fits all' and 'set and forget' approaches to nutrition do not adequately address the complex metabolic, hormonal, and immunological changes that occur with critical illness [3,5]. It is essential that clinicians understand these processes and the impact on nutrient metabolism [4].…”
Section: Introductionmentioning
confidence: 99%
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