Tailoring epilepsy treatment: personalized micro-physiological systems illuminate individual drug responses
Sanobar Shariff,
Burhan Kantawala,
William Xochitun Gopar Franco
et al.
Abstract:Introduction:
Approximately 50 million people worldwide have epilepsy, with many not achieving seizure freedom. Organ-on-chip technology, which mimics organ-level physiology, could revolutionize drug development for epilepsy by replacing animal models in preclinical studies. Our goal is to determine if customized micro-physiological systems can lead to tailored drug treatments for epileptic patients.
Materials and methods:
A comprehensive literature sea… Show more
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