Tailoring biomaterials for biomimetic organs-on-chips

Abstract

The advances in biomaterials for the construction of organs-on-chips are reviewed, including the design, fabrication, functions, applications, and future directions of these biomaterial-based platforms.

Bioengineering approaches for the endometrial research and application

“…Microfluidics are also regarded as microphysiological systems that simulate physiological states at the tissue or organ levels by controlling trace water flow, including interactions among tissues, microvascular perfusion, and physicochemical traits of microenvironments [ 41 ]. They can be used to illustrate cellular interactions by studying the mechanisms that produce these microscopic properties, particularly the shear forces and concentration gradients in the surroundings.…”

Semiconducting polymer dots for multifunctional integrated nanomedicine carriers

“…6 A). The current research focus in this field centers on two primary areas: ultra-high-resolution microscopic imaging of intricate subcellular spatial structures and macroscopic multi-dimensional analysis of multicellular structural tissue blocks [ [287] , [288] , [289] , [290] ]. This analysis ranges from two-dimensional (2D-conventional planar imaging) to three-dimensional (3D-stereo imaging), encompassing visualization of protein spatial conformation and noninvasive imaging of deep tissues [ 87 , 291 ].…”

Biosyncretic Robots Actuated by Living Materials

“…This technology holds immense potential in the field of biomedicine and is expected to be used in high‐throughput drug screening, new drug development, and biophysiological research. [ 126 ] Currently, organ‐on‐a‐chip systems have been developed using cardiomyocytes and skeletal muscle cells.…”