Abstract:Background: We evaluated the feasibility and the likelihood of achieving high response rates by tailoring neoadjuvant therapy based on individual patient and tumor characteristics. Triple negative (TNBC) and HER2+ pts were treated with chemotherapy. Hormone Receptor (HR)+ HER2-pts were treated based on the Oncotype DX Breast Recurrence Score (RS) result. Methods: Between 4/2013 and 1/2015, 40 pts with stage II (T > 2cm) or III were enrolled: 15 HER2+, 15 TNBC and 10 with HR + HER2-breast cancer with RS ≥25. HR… Show more
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