Tailor-made deep eutectic solvents-based green extraction of natural antioxidants from partridge leaf-tea (Mallotus furetianus L.)

Wang, Ruimin; He, Ruiping; Li, Zhaohui; Li, Songjie; Li, Congfa; Wang, Lu

doi:10.1016/j.seppur.2021.119159

Cited by 37 publications

(24 citation statements)

References 40 publications

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“…In addition, high R α-GIA = 0.9438) showed that there was a high consistency between predicted and measured values. The high adequacy precision (> 4.0) implied an adequate result of signal/noise, indicating high precision and reliability of the RSM mode [19,37]. In this study, high adequacy precision (AP) of 11.657, 10.900, 9.321, 20.811, and 10.304 was observed for TPC, TFC, ABTS +• , FRAP, and α-GIA, respectively.…”

Section: Modeling Of Uae Process Conditionssupporting

confidence: 49%

“…Wang et al [19] also verified that X 1 greatly influenced the viscosity and mass and energy transfer of extraction systems. An appropriate water content in DES can evidently enhance the extraction of phenolic compounds from DLT.…”

Section: Modeling Of Uae Process Conditionsmentioning

confidence: 94%

“…Mobile phases consisted of acetonitrile (A) and 0.1% formic acid-water (B), and the gradient elution program was set as follows: 0-5 min, 15% B; 5-25 min, 25-35% B; 25-40 min, 25-50% B; 40-45 min, 85% B; and 45-50 min, 15% B. The column temperature was 30 • C, flow rate was 0.8 mL/min, the injection volume was 10 µL, and the detection wavelength was carried out at 280 nm [19,20]. The contents of the identified phenolic compounds were expressed as µg/g DLT in dry weight.…”

Section: Hplc-dad Analysismentioning

confidence: 99%

“…Owing to their advantages of low costs, biodegradability, eco-friendliness, and non-toxicity, DESs have been increasingly applied in the extraction of bio-active compounds including phenolics, alkaloids, and saponins [15][16][17]. Currently, ultrasonic technique has been introduced into active compounds extraction because of its lower cost, high-efficiency, eco-friendliness, and easiness in scaling up [18,19]. On one hand, the cavitation effect caused by ultrasonication can rupture the cell wall structure, making more active compounds released from plant materials.…”

Section: Introductionmentioning

confidence: 99%

“…On the other hand, ultrasonic process can enhance the energy and mass transfer of extractives in solvent system by declining the diffusion boundary layers. Hence, the ultrasonic-assisted extraction (UAE) process using eco-friendly DESs is expected to enhance the extraction of active compounds from natural products [18][19][20]. However, there have been no reports on enhancing the extraction of phenolic antioxidants from DLT by using eco-friendly DESs-based UAE technique.…”

Section: Introductionmentioning

confidence: 99%

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Customized Deep Eutectic Solvents as Green Extractants for Ultrasonic-Assisted Enhanced Extraction of Phenolic Antioxidants from Dogbane Leaf-Tea

Wang

Zhang

et al. 2021

Foods

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This study evaluates the application of eco-friendly deep eutectic solvents (DESs) in the extraction of phenolic antioxidants from dogbane leaf-tea (DLT). The results showed DESs with lower viscosity allowed an efficient extraction of significantly higher contents of total phenolics or flavonoids. An innovative and high-efficient solvent, choline chloride-levulinic acid (ChCl-LevA), was screened and used in ultrasonic-assisted extraction (UAE) of phenolic compounds from DLT. According to full factorial design experimental results, total phenolic content (TPC), total flavonoid content (TFC), antioxidant activity, and anti-α-glucosidase activity (α-GIA) of the DLT extracts were simultaneously optimized by response surface methodology. Sonication temperature and water content in ChCl-LevA were found to be the major factors affecting the TPC, TFC, antioxidant activity, and α-GIA of DLT extracts. Under the optimum parameters (water content in ChCl-LevA was 45%, sonication temperature was 50 °C, and extraction time was 30 min), the measured results for all the responses were obtained as follows: TPC-91.38 ± 7.20 mg GAE/g DW, TFC-84.12 ± 3.47 mg RE/g DW, ABTS+-492 ± 7.33 mmol TE/g DW, FRAP-6235 ± 121 μmol Fe(II)/g DW and α-GIA-230 ± 7.59 mmol AE/g DW, which were consistent with the predicted values. In addition, strongly significant positive correlations were observed between TPC/TFC and bio-activities of the DLT extracts. HPLC results indicated high contents of (-)-epigallocatechin (4272 ± 84.86 μg/g DW), catechin (5268 ± 24.53 μg/g DW), isoquercitrin (3500 ± 86.07 μg/g DW), kaempferol 3-O-rutinoside (3717 ± 97.71 μg/g DW), and protocatechuic acid (644 ± 1.65 μg/g DW) were observed in the DLT extracts. In contrast to other extraction methods, ChCl-LevA-based UAE yielded higher TPC, TFC, individual phenolic contents, stronger antioxidant activity, and α-GIA. Scanning electron microscope (SEM) analysis further confirmed that ChCl-LevA-based UAE enhanced the disruption of cell wall structure, thereby making more phenolic antioxidants released from DLT. In short, ChCl-LevA-based UAE was confirmed to be an innovative and high-efficient method for extraction of phenolic antioxidants from DLT. Dogbane leaves can be considered as a good tea source rich in natural antioxidants.

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Section: Modeling Of Uae Process Conditionssupporting

confidence: 49%

Section: Modeling Of Uae Process Conditionsmentioning

confidence: 94%

Section: Hplc-dad Analysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Customized Deep Eutectic Solvents as Green Extractants for Ultrasonic-Assisted Enhanced Extraction of Phenolic Antioxidants from Dogbane Leaf-Tea

Wang

Zhang

et al. 2021

Foods

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Adsorption equilibrium, kinetics and dynamic process of polyphenols from orange peel extract on mixed‐mode adsorption resin HD‐1

Wang,

Jiao,

Dong

et al. 2024

J of Chemical Tech & Biotech

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BACKGROUNDThe extraction and separation of natural polyphenols are attractive. Many researchers used high‐speed counter‐current chromatography to separate and purify polyphenols. However, it requires a long operating time, a large amount of organic solvent consumption, and a high operating cost. In this work, the adsorption behaviors of polyphenols from the orange peel extract on mixed‐mode resins were studied. The adsorption capacities and selectivities of different resins to the main polyphenols in the extract including gallic acid, p‐coumaric acid, and ferulic acid were compared. The adsorption mechanism was analyzed by adsorption equilibrium and kinetics studies as well as molecular docking. The fixed‐bed adsorption was studied experimentally and theoretically.RESULTSHD‐1 resin had excellent adsorption selectivities among the resins. The yield of polyphenols from the orange peel by integrated extraction‐adsorption increased by 82.94% compared with that of extraction without adsorption. The adsorption isotherms agreed with Freundlich model. Dubinin‐Radushkevich model results indicated that the adsorption of gallic acid mainly depends on non‐electrostatic interaction. The adsorption of the other two polyphenols involves electrostatic and non‐electrostatic interaction. The adsorption kinetics curves accorded with pseudo‐second‐order model, and the adsorption rate of gallic acid was the highest among the polyphenols. Adsorption of polyphenols involves both physical adsorption and chemical adsorption. The breakthrough curves could be well simulated by Yoon‐Nelson and Thoms models. Significant differences exist in times for 50% breakthrough.CONCLUSIONThe mixed‐mode chromatography with HD‐1 resin as stationary phase is applicable to separate the polyphenols.This article is protected by copyright. All rights reserved.

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Developing a recovery process for bioactives from discarded by‐products of winemaking industry based on multivariate optimization method: Deep eutectic solvents as eco‐friendly extraction media

Kavas,

Erbaşar,

Kurtulbaş

et al. 2024

Phytochemical Analysis

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IntroductionThe recovery process for bioactives from discarded by‐products of the winemaking industry is of great value considering both environmental and economic aspects.ObjectiveThe goal of this study is to investigate the extraction of phenolic antioxidants from grape (Vitis vinifera) seeds by means of carboxylic acid‐based deep eutectic solvents (DESs) in order to propose an environmentally friendly method based on a multivariate optimization approach.Material and MethodsCarboxylic acid‐based DESs were designed with several molar ratios (1/1, 1/2, and 2/1). Two polyols (glycerol and ethylene glycol) were used as hydrogen bond donors, while formic acid, acetic acid, and propionic acid were selected as hydrogen bond acceptors. The process parameters (water content, extraction time, and solid mass) were analyzed to optimize the process through Box–Behnken design with response surface method, after determination of the best combination for the highest total phenolic content (TPC) and the antioxidant activity yields.ResultsThe maximum TPC yield (153.17 ± 0.003 mg‐GAE/g‐GS) and antioxidant activity yield (82.26 ± 0.004 mg‐GAE/g‐GS) were achieved by 50% water addition into the DES (ethylene glycol/acetic acid, 1/1), 85 sec extraction time, and 0.1 g grape seed.

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Tailor-made deep eutectic solvents-based green extraction of natural antioxidants from partridge leaf-tea (Mallotus furetianus L.)

Cited by 37 publications

References 40 publications

Customized Deep Eutectic Solvents as Green Extractants for Ultrasonic-Assisted Enhanced Extraction of Phenolic Antioxidants from Dogbane Leaf-Tea

Customized Deep Eutectic Solvents as Green Extractants for Ultrasonic-Assisted Enhanced Extraction of Phenolic Antioxidants from Dogbane Leaf-Tea

Adsorption equilibrium, kinetics and dynamic process of polyphenols from orange peel extract on mixed‐mode adsorption resin HD‐1

Developing a recovery process for bioactives from discarded by‐products of winemaking industry based on multivariate optimization method: Deep eutectic solvents as eco‐friendly extraction media

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