Tailings From a Lead Mine and Lead Levels in Schoolchildren: A Preliminary Report

Heyworth, F; Spickett, Jeffery; Dick, Matthew H.; Margetts, B.; Armstrong, Beth L.

doi:10.5694/j.1326-5377.1981.tb100932.x

Cited by 19 publications

(2 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Plus, the high calcium content of Derbyshire soils limits applicability of results to other site soils. Heyworth et al (1981) reported that an Australian town with widely dispersed lead-mill tailings showed statistically significant higher Pb-B levels in the town's children compared to a reference town without mill tailings. The significant difference was seen despite the fact that three-quarters of the tailing town children were over seven years of age; younger children in the 2-4 years age range who ingest larger amounts of dust and soil would be expected to show an even more robust response.…”

Section: Referencementioning

confidence: 99%

Gastro-Intestinal Absorption of Lead in Children and Adults: Overview of Biological and Biophysico-Chemical Aspects

Mushak

1991

Chemical Speciation & Bioavailability

102

View full text Add to dashboard Cite

Intake and uptake of lead in the general population is mainly via the gastro-intestinal (GI) tract. Those biological and biophysico-chemical factors operating in the Gl tract are the main determinants of Pb bioavailability. They include sites of Pb uptake, the physiology of uptake/transport to blood, the stage of development, interactions of Pb with nutrients, and Gl biochemical transformations of ingested material. Lead uptake occurs as ion or complex, from micelles and perhaps by pinocytosis in the infant. Uptake is mainly via the duodenum but other sites can participate, e.g. ileum (pinocytosis) and colon. Transport to blood is by active, carrier-mediated transport and passive diffusion. Uptake may include movement through intercellular tight junctions. Lead uptake is affected by nutrients in the Gl tract, operating synergistically or antagonistically. Iron and calcium interactions are most important and augment those also occurring in vivo in tissues. Liberation of lead from diverse ingested media, e.g. food, paint, soil and dust, mining waste, is affected by their chemical/physical forms, hydrolytic and oxidative processes in gastric fluid and other Gl sites. Such changes in vivo are poorly simulated by in vitro tests. The downward revision of blood lead (Pb-8) levels considered 'safe', to about 0.5 ~mol C 1 (10 ~g dL-t) or lower, causes even sources of moderately bioavailable Pb to become important.

show abstract

Section: Referencementioning

confidence: 99%

Gastro-Intestinal Absorption of Lead in Children and Adults: Overview of Biological and Biophysico-Chemical Aspects

Mushak

1991

Chemical Speciation & Bioavailability

102

View full text Add to dashboard Cite

show abstract

“…Το χώμα μιας περιοχής μπορεί να περιέχει μεγάλες ποσότητες Pb, επειδή υπάρχει μετάλλευμα Pb στη περιοχή, ή παλιά αποφρίγματα μεταλλουργείου (Barltrop et al, 1974, Heyworth et al, 1981.…”

Section: στις βιομηχανικές χώρες οι συγκεντρώσεις ατμοσφαιρικούunclassified

Επιπεδα Μολυβδου Αιματος Και Νεφρικη Λειτουργια Παιδιων Μιας Περιοχης Με Αυξημενο Περιβαλλοντικο Μολυβδο

Νακου¹

View full text Add to dashboard Cite

show abstract

The Internal Burden of Lead among Children in a Smelter Town—A Small Area Analysis

Trepka

Heinrich

Krause

et al. 1997

Environmental Research

View full text Add to dashboard Cite

Tailings From a Lead Mine and Lead Levels in Schoolchildren: A Preliminary Report

Cited by 19 publications

References 5 publications

Gastro-Intestinal Absorption of Lead in Children and Adults: Overview of Biological and Biophysico-Chemical Aspects

Gastro-Intestinal Absorption of Lead in Children and Adults: Overview of Biological and Biophysico-Chemical Aspects

Επιπεδα Μολυβδου Αιματος Και Νεφρικη Λειτουργια Παιδιων Μιας Περιοχης Με Αυξημενο Περιβαλλοντικο Μολυβδο

The Internal Burden of Lead among Children in a Smelter Town—A Small Area Analysis

Contact Info

Product

Resources

About