Taf7l Regulates Early Stages of Male Germ Cell Development
Ayelen Moreno-Irusta,
Esteban M. Dominguez,
Khursheed Iqbal
et al.
Abstract:Male germ cell development is dependent on the orchestrated regulation of gene networks. TATA-box binding protein associated factors (TAFs) facilitate interactions of TATA-binding protein with the TATA element, which is known to coordinate gene transcription during organogenesis. TAF7 like (Taf7l) is situated on the X chromosome and has been implicated in testis development. We examined the biology of TAF7L in testis development using the rat.Taf7lwas prominently expressed in preleptotene to leptotene spermato… Show more
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