Taeniasis/cysticercosis trend worldwide and rationale for control

Montresor, Antonio; Palmer, Kevin

doi:10.1016/j.parint.2005.11.045

Cited by 25 publications

(13 citation statements)

References 15 publications

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“…[7,27] Due to the zoonotic nature of taeniasis/cysticercosis, its control must also include the veterinary sector. [4,28] At present, only four drugs are recommended by the World Health Organization (WHO) for treating STH infections. [27] The global STH control relies on two of them-albendazole and mebendazole -both benzimidazole carbamates.…”

Section: To Assess the Efficacy And Safety Of Various Anti-heliminthimentioning

confidence: 99%

To Assess the Efficacy and Safety of Various Anti-heliminthics against Ascariasis Lumbricoides among a Study Population in North India

Kawoosa¹,

Javid²,

Yattoo³

et al. 2018

OGH Reports

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Introduction: More than 24% of the world's population, are infected with soil-transmitted helminth infection. Aim: To assess the helminthic load & efficacy and safety of various antiheliminthics. Methods: A total of 400 patients who met the inclusion criteria were recruited after proper consent. Subjects were divided into Four groups (100 each) randomly & receive different anti-helminthic drugs. Cure rate and egg reduction rate was used as a primary outcome measure. Three weeks later two more stool samples were analyzed by two methods 1) Direct Smear method & 2) Concentration method. On follow-up, each group were randomly assigned a single dose of albendazole (single 400 mg dose), mebendazole (100 mg, BD×3 days), pyrantel pamoate (11 mg/kg orally once) and ivermectin (0.2 mg/kg orally once) using a randomization procedure.The data was statistically analysed. Observations: Among 400 patients, 63% were 5-19 years of age, 68% were male, 73.5% were from rural areas, 71% were literate, 62% were in the low income group, 58% reported closed sanitation, 6.75% were having low BMI, 26.25% were having High Absolute Eosinophilic Count before treatment, 77.5% were non-anaemic. 92.5% did not have icterus.In the present study it was seen that the difference among the four drugs was statistically significant as per demographic variables. Significant decrease of worm load after treatment were comparable with each other. However, Presence of Worm across papillae seen after upper GI endoscopy and persistent biliary ascariasis was comparable in all the four drug groups. Overall, the efficacy of anthelmintic drugs was excellent and statistically significant (p<0.001). Conclusion: Albendazole and mebendazole having cure rates of 90% and also reducing the mean egg count by 90%. Also treatment of school children every 4 monthly may be necessary in high endemic areas, like ours. All these drugs which we used in our study are safe and no significant side effects were observed.

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Section: To Assess the Efficacy And Safety Of Various Anti-heliminthimentioning

confidence: 99%

To Assess the Efficacy and Safety of Various Anti-heliminthics against Ascariasis Lumbricoides among a Study Population in North India

Kawoosa¹,

Javid²,

Yattoo³

et al. 2018

OGH Reports

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“…For such actions, we need international collaborators who are willing to join us with high appreciation of the local contribution. We sincerely do expect that such encouragement for meaningful international collaborations may be available from both FAO [32] and WHO [33].…”

Section: Function Of Fao and Whomentioning

confidence: 99%

Brief historical remarks as an introduction for the international symposium on taeniasis/cysticercosis and echinococcosis

Itō

2006

Parasitology International

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“…Cysticercosis (CC) is a parasitic tissue infection caused by larval cysts of the pork tapeworm Taenia solium [ 1 ]. Pigs, the CC natural intermediate hosts, become infected by eating tapeworm eggs in the feces of a human infected with a tapeworm.…”

Section: Introductionmentioning

confidence: 99%

Clinical Cysticercosis epidemiology in Spain based on the hospital discharge database: What's new?

et al. 2018

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BackgroundCysticercosis (CC) is a tissue infection caused by the larval cysts of the pork tapeworm Taenia solium. It is usually acquired by eating contaminated food or drinking water. CC Cysts can develop in the muscles, the eyes, the brain, and/or the spinal cord. T. solium is found worldwide, but its prevalence has decreased in developed countries due to stricter meat inspection and better hygiene and sanitation. Nevertheless, CC is still a leading cause of seizures and epilepsy. In Spain, The disease is not nationally reportable and data on CC infected animals are also missing, despite the European Directive 2003/99/EC.Methodology/Principal findingsWe performed a retrospective descriptive study using the Spanish Hospitalization Minimum Data Set (CMBD). Data with ICD-9 CM cysticercosis code (“123.1”) placed in first or second diagnostic position from 1997 to 2014 were analyzed. Hospitalization rates were calculated and clinical characteristics were described. Spatial distribution of cases and their temporal behavior were also assessed. A total of 1,912 hospital discharges with clinical cysticercosis were identified. From 1998 to 2008, an increasing trend in the number of CC hospitalizations was observed, decreasing afterwards, in parallel with a decrease in the external migration rate. The Murcia region had the highest median hospitalization rate (13.37 hospitalizations/100,000 population), followed by Navarra and Madrid. The 16–44 age group was the most represented (63.6%). The three most frequent associated diagnoses were epilepsy and convulsions (49.5%), hydrocephalus (11.8%) and encephalitis/myelitis/meningitis (11.6%).Conclusions/SignificanceThere is a need for a common strategy on data collection, monitoring and reporting, which would facilitate a more accurate picture on the CC epidemiological scenario. Even if most cases might be imported, improving the human and animal CC surveillance will result useful both in gaining extended disease knowledge and reducing morbidity and related-costs.

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Taeniasis/cysticercosis trend worldwide and rationale for control

Cited by 25 publications

References 15 publications

To Assess the Efficacy and Safety of Various Anti-heliminthics against Ascariasis Lumbricoides among a Study Population in North India

To Assess the Efficacy and Safety of Various Anti-heliminthics against Ascariasis Lumbricoides among a Study Population in North India

Brief historical remarks as an introduction for the international symposium on taeniasis/cysticercosis and echinococcosis

Clinical Cysticercosis epidemiology in Spain based on the hospital discharge database: What's new?

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