Taeniasis/cysticercosis in a Tibetan population in Sichuan Province, China

Li, Tiaoying; Craig, Philip S.; Itō, Akira; Chen, Xingwang; Qiu, Dongchuan; Qiu, Jiamin; Sato, Marcello Otake; Wandra, Toni; Bradshaw, Helen; Li, L i; Yang, Yun; Wang, Qian

doi:10.1016/j.actatropica.2006.11.003

Cited by 69 publications

(63 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The prevalence of T. saginata recorded in this study based on the questionnaire (50.6%) illustrated the significance of taeniasis in the population of Wolaita Soddo town and it is very close to the findings of Abunna et al (2007) (64.2%) and Dawit (2004) (69.2%) in Ethiopia. On the other hand, Li et al (2006) reported relatively lower prevalence (22.5%) in china.…”

Section: Discussionmentioning

confidence: 73%

Major metacestodes in cattle slaughtered at Wolaita Soddo Municipal abattoir, Southern Ethiopia: Prevalence, cyst viability, organ distribution and socioeconomic implications

Regassa

Abunna

Mulugeta

et al. 2009

Trop Anim Health Prod

View full text Add to dashboard Cite

A cross sectional study to determine the prevalence and socioeconomic importance of major metacestodes of cattle was conducted from November 2007 to April 2008 at Wolaita Soddo abattoir. Accordingly, of 415 randomly selected slaughtered cattle, 11.3% and 15.4% were infected with Cysticercus bovis and hydatid cysts, respectively. The anatomical distributions of these parasites include various organs. The major risk factors for cysticercosis prevalence were origin of the animals (P < 0.001, OR = 7.3) and breeds (P = 0.004, OR = 4.3), and hydatid cysts prevalence was significantly varied with different origins (P = 0.021, OR = 2.8). The viability of C. bovis was higher (28.3%) than that of hydatid cyst (1.7%). Of 79 interviewed respondents, 50.63% had acquired taeniasis and analysis of the risk factors showed association of religions (P = 0.003, OR = 24.4), occupation (P < 0.001, OR = 6.9), educational background (P = 0.035, OR = 2.7) and age (P < 0.001, OR = 3.9) of the respondents with taeniasis prevalence. Furthermore, the inventory of taeniasis drugs dose and treatment cost were estimated to be 335,772 adult doses and 93,310 USD. In conclusion, the findings of the present study imply the zoonotic and socioeconomic importance of the diseases, which need intervention.

show abstract

Section: Discussionmentioning

confidence: 73%

Major metacestodes in cattle slaughtered at Wolaita Soddo Municipal abattoir, Southern Ethiopia: Prevalence, cyst viability, organ distribution and socioeconomic implications

Regassa

Abunna

Mulugeta

et al. 2009

Trop Anim Health Prod

View full text Add to dashboard Cite

show abstract

“…Fecal and/or parasite samples used for this study were obtained through joint projects on epidemiological studies of taeniasis/cysticercosis in Indonesia, Thailand, and China (3,11,24). We sincerely thank T. Wandra, J. Waikagul, and T. Y. Li for their great help with these samplings.…”

Section: Acknowledgmentsmentioning

confidence: 99%

Loop-Mediated Isothermal Amplification Method for Differentiation and Rapid Detection of Taenia Species

Nkouawa

Sako²,

Nakao³

et al. 2009

J Clin Microbiol

Self Cite

112

View full text Add to dashboard Cite

Rapid detection and differentiation of Taenia species are required for the control and prevention of taeniasis and cysticercosis in areas where these diseases are endemic. Because of the lower sensitivity and specificity of the conventional diagnosis based on microscopical examination, molecular tools are more reliable for differential diagnosis of these diseases. In this study, we developed and evaluated a loopmediated isothermal amplification (LAMP) assay for differential diagnosis of infections with Taenia species with cathepsin L-like cysteine peptidase (clp) and cytochrome c oxidase subunit 1 (cox1) genes. LAMP with primer sets to the cox1 gene could differentiate between three species, and LAMP with primer sets to the clp gene could differentiate Taenia solium from Taenia saginata/Taenia asiatica. Restriction enzyme digestion of the LAMP products from primer set Tsag-clp allowed the differentiation of Taenia saginata from Taenia asiatica. We demonstrated the high specificity of LAMP by testing known parasite DNA samples extracted from proglottids (n ‫؍‬ 100) and cysticerci (n ‫؍‬ 68). LAMP could detect one copy of the target gene or five eggs of T. asiatica and T. saginata per gram of feces, showing sensitivity similar to that of PCR methods. Furthermore, LAMP could detect parasite DNA in all taeniid egg-positive fecal samples (n ‫؍‬ 6). Due to the rapid, simple, specific, and sensitive detection of Taenia species, the LAMP assays are valuable tools which might be easily applicable for the control and prevention of taeniasis and cysticercosis in countries where these diseases are endemic.

show abstract

“…The domestic animals always clean human feces by eating. This is very different from the customs of the Han people, the majori- Reports of other researchers give more information on the distribution of T. asiatica by finding out 2 cases from Lanping County, Yunnan Province which was confirmed by morphological observation and experimental infection in intermediate host animals [16]; Dali of Yunnan Province and Duyun of Guizhou Province by mitochondrial CoxI analysis of the worms [17]; and 3 cases from Tibet of Sichuan by DNA genotyping [18].…”

Section: Chinamentioning

confidence: 99%