Tackling neurodegeneration in vitro with omics: a path towards new targets and drugs
Caterina Carraro,
Jessica V. Montgomery,
Julien Klimmt
et al.
Abstract:Drug discovery is a generally inefficient and capital-intensive process. For neurodegenerative diseases (NDDs), the development of novel therapeutics is particularly urgent considering the long list of late-stage drug candidate failures. Although our knowledge on the pathogenic mechanisms driving neurodegeneration is growing, additional efforts are required to achieve a better and ultimately complete understanding of the pathophysiological underpinnings of NDDs. Beyond the etiology of NDDs being heterogeneous … Show more
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