Tachycardiomyopathy Complicated by Focal Atrial Tachycardia: Incidence, Risk Factors, and Long‐Term Outcome

Ju, Weizhu; Yang, Bing; Li, Mingfang; Zhang, Fengxiang; Chen, Hongwu; Gu, Kai; Yu, Jinbo; Cao, Kejiang; Chen, Minglong

doi:10.1111/jce.12428

Cited by 29 publications

(30 citation statements)

References 37 publications

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“…Atrial fibrillation (AF) is present in 10% to 50% of patients with HF; many patients with cardiomyopathy and AF have worsening symptoms and ventricular function due solely to poorly-controlled ventricular rates (4). In 2 studies of adult patients with focal atrial tachycardia (AT), the incidence of AIC was 8.3% to 10% (5,6), whereas in a pediatric multicenter study of atrial ectopic tachycardia (AET), 28% had AIC (7). The incidence of AIC was 9% to 34% in patients with frequent premature ventricular complexes (PVCs) and/or nonsustained ventricular tachycardia referred for electrophysiological evaluation (8–10).…”

Section: Epidemiologymentioning

confidence: 99%

“…A curative strategy by catheter ablation should be pursued whenever possible as first-line therapy for supraventricular tachycardia-mediated AIC. Successful catheter ablation can normalize LVEF and is usually associated with excellent long-term outcomes (5,6). …”

Section: Aic Associated With Specific Arrhythmias In Adultsmentioning

confidence: 99%

“…Sudden cardiac death has been reported in AIC patients following symptom recovery and LVEF normalization (1,6,129). Nerheim et al reported 3 patients with AF-mediated AIC who died suddenly during follow-up while asymptomatic and having preserved LVEF and good functional status.…”

Section: Risk Of Sudden Deathmentioning

confidence: 99%

“…A follow-up cardiac MRI for assessment of residual fibrosis/scar could provide valuable prognostic information (128). Arrhythmia recurrence can be devastating (1,6,129). …”

Section: Risk Of Sudden Deathmentioning

confidence: 99%

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Arrhythmia-Induced Cardiomyopathies

Gopinathannair

Etheridge

Marchlinski

et al. 2015

Journal of the American College of Cardiology

295

116

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Arrhythmia-induced cardiomyopathy (AIC) is a potentially reversible condition in which left ventricular dysfunction is induced or mediated by atrial or ventricular arrhythmias. Cellular and extracellular changes in response to the culprit arrhythmia have been identified, but specific pathophysiological mechanisms remain unclear. Early recognition of AIC and prompt treatment of the culprit arrhythmia using pharmacological or ablative techniques results in symptom resolution and recovery of ventricular function. Although cardiomyopathy in response to an arrhythmia may take months to years to develop, recurrent arrhythmia can result in rapid decline in ventricular function with development of heart failure, suggesting residual ultrastructural abnormalities. Reports of sudden death in patients whose left ventricular ejection fraction have normalized cast doubt on the complete reversibility of this condition. Several aspects of AIC, including specific pathophysiological mechanisms, predisposing factors, optimal therapeutic strategies to prevent ultrastructural changes, and long-term risk of sudden death remain unresolved and need further research.

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Section: Epidemiologymentioning

confidence: 99%

Section: Aic Associated With Specific Arrhythmias In Adultsmentioning

confidence: 99%

Section: Risk Of Sudden Deathmentioning

confidence: 99%

“…A follow-up cardiac MRI for assessment of residual fibrosis/scar could provide valuable prognostic information (128). Arrhythmia recurrence can be devastating (1,6,129). …”

Section: Risk Of Sudden Deathmentioning

confidence: 99%

See 2 more Smart Citations

Arrhythmia-Induced Cardiomyopathies

Gopinathannair

Etheridge

Marchlinski

et al. 2015

Journal of the American College of Cardiology

295

116

View full text Add to dashboard Cite

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“…Thus, besides heart rate, the duration and persistence of tachycardia seems to be an important determinant. 43 TIC can occur at any age. It has been documented in fetuses (24 to 33 weeks in gestation) with persistent supraventricular tachycardia, 44 with resolution occurring following intrauterine cardioversion.…”

Section: Tachycardia-induced Cardiomyopathymentioning

confidence: 99%

Reversible Dilated Cardiomyopathy: Into the Thaumaturgy of the Heart—Part 1

et al. 2016

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Dilated cardiomyopathy (DCM) is a genetic or acquired heart muscle disorder characterized by dilation and impaired contraction of one or both ventricles. In the acquired forms of the disease, if the pathogenic agent is persistent, undiagnosed or untreated, permanent ultrastructural and morphological changes may lead to irreversible dysfunction. Conversely, when DCM is promptly recognized and treated, the heart may show an extraordinary ability to recover from left ventricular (LV) systolic dysfunction. While much research in heart failure has focused on morbidity and mortality associated with persistent LV systolic dysfunction, relatively little attention has been devoted to this remarkable potential for recovery. In this two-part review we will focus on the most common types of reversible DCM. The first part will deal with Tako-Tsubo cardiomyopathy, tachycardiainduced cardiomyopathy, metabolic DCM and recovery after Left ventricular assist device implantation. Although diverse in etiopathogenesis, genetic background, therapeutic options and outcome, the forms of DCM characterized by reversible LV dysfunction share similar challenges in diagnosis and clinical management. The identification of pathways to recovery may show the way for novel therapeutic targets ultimately benefitting all cardiac patients.

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