Tables of the Freeman-Tukey Transformations for the Binomial and Poisson Distributions

Mosteller, Frederick; Youtz, Cleo

doi:10.2307/2332765

Cited by 48 publications

(34 citation statements)

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“…For the meta-analysis, the proportions of the individual studies were Freeman–Tukey transformed [35] to enable the application of the common methods for fixed and random effects [6]. The pooled proportion was then calculated by inverse transformation of the weighted averages of the transformed proportions.…”

Section: Methodsmentioning

confidence: 99%

Hemorrhage rate after coblation tonsillectomy: a meta-analysis of published trials

Mösges

Hellmich

Allekotte

et al. 2011

Eur Arch Otorhinolaryngol

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After the surgical procedure of tonsillectomy, hemorrhage ranks among its serious postoperative complications. In this systematic review, we analyze hemorrhage following tonsillectomies performed using the coblation technique. 24 prospective, randomized, and controlled studies were included in the meta-analysis. Data of 796 patients who had undergone coblation tonsillectomy were analyzed. Hemorrhages occurred in 33 patients: 2 classified as primary and 26 as secondary hemorrhages. 5 could not be classified into either group. Overall, the total hemorrhage rate for the coblation procedure was 4.1% with a 95% confidence interval from 2.8 to 5.5%. The overall hemorrhage rate of 4.1% found in this meta-analysis shows that coblation is a safe and effective technique for tonsillectomies with a secondary bleeding rate similar to what is reported for comparable techniques such as bipolar diathermia.

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Section: Methodsmentioning

confidence: 99%

Hemorrhage rate after coblation tonsillectomy: a meta-analysis of published trials

Mösges

Hellmich

Allekotte

et al. 2011

Eur Arch Otorhinolaryngol

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“…Data transformations were employed to stabilize variance and to improve distribution normality in non-normally distributed data. The Freeman-Tukey transformation, a double arcsine transformation, was used to convert binomial counts to working quantities prior to analyses designed to fit normally distributed data 10. Independent binomial proportions were transformed prior to calculation of a pooled proportions estimate.…”

Section: Methodsmentioning

confidence: 99%

Frequency of mismatch repair deficiency in ovarian cancer: a systematic review This article is a US Government work and, as such, is in the public domain of the United States of America.

Murphy

Wentzensen

2011

Intl Journal of Cancer

107

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Loss of mismatch repair (MMR) capacity may represent an important tumor initiating mechanism in ovarian cancer. We conducted a systematic review to analyze the frequency of microsatellite instability (MSI), immunohistochemical (IHC) staining for MMR proteins, and hypermethylation of the MLH1 promoter region in ovarian cancers. Studies examining MSI, loss of MMR gene expression by IHC staining and MLH1 promoter hypermethylation in ovarian cancer were identified by a systematic literature search of the PubMed electronic database through August 31, 2009. Pertinent data was extracted from eligible studies and estimates for pooled proportions were computed using random effects models. The pooled proportion of MSI detection was 0.10 (95% CI, 0.0620.14) among 1,234 cases in 22 studies. Dinonucleotide markers had a higher frequency of instability than mononucleotide markers. The pooled proportion of MLH1 or MSH2 staining loss was 0.06 (95% CI, 0.0120.17) among 474 cases in three studies, with a higher frequency of loss in MLH1. The pooled proportion of MLH1 methylation was 0.10 (95% CI, 0.0620.15) among 672 cases in seven studies. Data reporting MSI and loss of MMR staining in the same cases was limited. Although MMR deficiency was found in all histologic subtypes, endometrioid cancers had the highest proportion. Approximately 10% of unselected ovarian cancers are related to MMR deficiency. While MMR deficiency is associated with improved survival in other MMR-deficiency related cancer sites, epidemiological and clinical factors related to the MMR-deficient phenotype have not been adequately studied in ovarian cancer to date.Ovarian cancer is responsible for more deaths annually than any other female reproductive cancer. In the United States, one out of seventy females will develop this malignancy in their lifetime. Because early detection is difficult, most women present with late-stage disease, which contributes to a low overall 5-year survival rate, of only 45%. A limited number of ovarian cancer risk factors have been identified to date; neither the etiology nor the pathogenesis is well understood. While several histologic subtypes can be distinguished, it is not clear how these subtypes relate to risk factors or molecular pathways.

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“…The percentage hen-day production (%HDP) of normal, defective and total eggs were transformed to arc sinV% prior to analysis. Freeman-Tukey arc sins were obtained for proportions based on less than 50 observations (Mosteller and Youtz, 1961). Comparisons among means were by Duncan's multiple range test.…”

Section: Methodsmentioning

confidence: 99%

Selection for Body Weight at Eight Weeks of Age

Siegel

1976

Poultry Science

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Two experiments were conducted to study oviposition patterns and ovarian activity at various physiological ages in S15 and S16 generation pullets from lines selected bidirectionally for high (HWS) and low (LWS) juvenile body weight. The fixed periods of lay for random samples of pullets from the date of first egg were 20, 40, 60, and 80 days in the first experiment and 40, 80, 120, and 160 days in the second experiment. HWS pullets matured significantly earlier than LWS pullets in both generations. The frequency and the percentage hen-day production (%HDP) of defective eggs were significantly greater in the HWS than LWS line in both generations. Delayed sexual maturity did not significantly change the pattern of defective egg production for a fixed period of lay. In the HWS line the %HDP of defective eggs progressively increased until about 40 days of lay and tended to decline thereafter, while in the LWS line the percentage decreased from 20 to 40 days and then stabilized. The frequency of normal unbroken eggs to 80 days of production did not differ among lines either in the S15 or S16 generation. When measurements were extended to 160 days of lay in the S16 generation HWS pullets produced significantly more normal eggs than LWS pullets. Possible effects of ovarian activity on the egg production pattern during the laying cycle are discussed. There was a significantly higher incidence of internal laying and atrecia of the growing follicles in the HWS than in the LWS pullets. Ovarian activity, evidenced by the number of developing and ruptured follicles, was significantly greater in the HWS than the LWS line, as was the incidence of ova developing in pairs. Product moment correlations and multiple regressions among the measurements of ovarian activity were calculated within lines. In the HWS line, 62.5% of the variation in %HDP of defective eggs could be accounted for by the %HDP of normal eggs and the number of developing follicles while in the LWS line these variables accounted for only 7.29% of the variation in %HDP of defective eggs.

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Tables of the Freeman-Tukey Transformations for the Binomial and Poisson Distributions

Cited by 48 publications

References 1 publication

Hemorrhage rate after coblation tonsillectomy: a meta-analysis of published trials

Hemorrhage rate after coblation tonsillectomy: a meta-analysis of published trials

Frequency of mismatch repair deficiency in ovarian cancer: a systematic review This article is a US Government work and, as such, is in the public domain of the United States of America.

Selection for Body Weight at Eight Weeks of Age

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