T2- and diffusion-weighted magnetic resonance imaging at 3 T for the detection of prostate cancer with and without endorectal coil: An intraindividual comparison of image quality and diagnostic performance

Baur, Alexander; Daqqaq, Tareef S; Wagner, Moritz; Maxeiner, Andreas; Huppertz, Alexander; Renz, Diane M.; Hamm, Bernd; Fischer, Thomas; Durmus, Tahir

doi:10.1016/j.ejrad.2016.03.014

Cited by 37 publications

(41 citation statements)

References 19 publications

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“…The ERC image set showed a tendency towards higher sensitivity as compared to the image set acquired with the PPA receiver coil only, however, differences were not statistically significant. Another recent study supports our findings by demonstrating insignificant differences between receiver coil setups for the detection of index lesions [11]. Our achieved sensitivities of 0.76-0.97 on a per patient basis, are lower than the achieved sensitivities in the aforementioned study (0.96-0.97).…”

Section: Discussioncontrasting

confidence: 54%

“…For 3T scanners and pelvic phased array (PPA) receiver coil equipment, the situation is not as clear. While it has been shown that using comparable sequence parameters, similar image quality for ERC and surface receiver coil (SRC) may be achieved [10], other studies [11,12,13] have demonstrated similar diagnostic accuracy with both coil settings despite lower image quality achieved with the SRC configuration. These studies however, did not investigate the diagnostic performance of a complete mpMRI protocol consisting of T2-weighted (T2w), diffusion-weighted imaging (DWI) and dynamic contrast enhanced (DCE) images and did not use whole-mount histopathology as the standard of reference.…”

Section: Introductionmentioning

confidence: 99%

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Diagnostic Accuracy of a MR Protocol Acquired with and without Endorectal Coil for Detection of Prostate Cancer: A Multicenter Study

Barth¹,

Rupp²,

Cornelius³

et al. 2019

Current Urology

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Introduction: The purpose of this study was to compare diagnostic accuracy of a prostate multiparametric magnetic resonance imaging (mpMRI) protocol for detection of prostate cancer between images acquired with and without en-dorectal coil (ERC). Materials: This study was approved by the regional ethics committee. Between 2014 and 2015, 33 patients (median age 51.3 years; range 42.1-77.3 years) who underwent prostate-MRI at 3T scanners at 2 different institutions, acquired with (mpMRI_ERC) and without (mpMRI_PPA) ERC and who received radical prostatectomy, were included in this retrospective study. Two expert readers (R1, R2) attributed a PI-RADS version 2 score for the most suspect (i. e. index) lesion for mpMRI_PPA and mpMRI_ERC. Sensitivity and positive predictive value for detection of index lesions were assessed using 2 × 2 contingency tables. Differences between groups were tested using the McNemar test. Whole-mount histopathology served as reference standard. Results: On a quadrant-basis cumulative sensitivity ranged between 0.61-0.67 and 0.76-0.88 for mpMRI_PPA and mpMRI_ERC protocols, respectively (p > 0.05). Cumulative positive predictive value ranged between 0.80-0.81 and 0.89-0.91 for mpMRI_PPA and mpMRI_ERC protocols, respectively. The differences were not statistically significant for R1 (p = 0.267) or R2 (p = 0.508). Conclusion: Our results suggest that there may be no significant differences for detection of prostate cancer between images acquired with and without an ERC.

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Section: Discussioncontrasting

confidence: 54%

Section: Introductionmentioning

confidence: 99%

Diagnostic Accuracy of a MR Protocol Acquired with and without Endorectal Coil for Detection of Prostate Cancer: A Multicenter Study

Barth¹,

Rupp²,

Cornelius³

et al. 2019

Current Urology

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“…Within the performance of prostate MRI the same considerations impact the utility of the exam, but studies utilizing differing MRI modalities [e.g., 1.5 Tesla MRI without endorectal coil (40) versus 3 Tesla MRI with endorectal coil (41,42)] are often referred to without explicit differentiation. Both coil type and field strength have been shown to impact image quality (43) and more modern, higher field strength scanners are more expensive.…”

Section: Considerations and Limitations In Prostate Mri Literaturementioning

confidence: 99%

Cost consideration in utilization of multiparametric magnetic resonance imaging in prostate cancer

Hutchinson

Lotan²

2017

Transl. Androl. Urol.

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The screening, evaluation and management of prostate cancer changed significantly in the last decade. The recommendations regarding prostate cancer screening continue to evolve with new revelations about existing data sets and longer followup of landmark trials. Robotics has gained the vast majority of the marketplace for surgically managed prostate cancer in rapid fashion. The need for intervention in low risk prostate cancer has been closely examined and more men are being expectantly managed than ever before. Amidst all these changes, prostate magnetic resonance imaging (MRI) has emerged as a disruptive technology. Through the use of dynamic contrast-enhanced and diffusion weighted series, prostate tumors that were previously not visible have become identifiable and quantifiable. The ability of MRI to improve staging and identification of clinically significant disease has resulted in increased utilization for different aspects of prostate cancer care. The best studied use is in men with a prior negative transrectal ultrasound guided (TRUS) prostate biopsy and the performance characteristics in this role match well with the clinical question raised. The role for MRI in initial biopsy, in pre-surgical planning before prostatectomy and in men on active surveillance is less well defined. A primary concern in the use of MRI is that of cost. MRI units are expensive, both in initial outlay and ongoing use. The availability of MRI varies widely between countries and even within regions of the same country. Different healthcare models have different approaches for allocating the use of expensive resources, including MRI, in times when they are scarce. Prostate MRI can be used at multiple points in the management algorithm of prostate cancer and each implies different cost concerns. In this review we present an overview of current research in cost and cost efficacy for the use of MRI in the management of prostate cancer. By examining what is known and highlighting areas of ongoing research we hope to provide the reader with a solid foundation for understanding these complex, ever-changing issues.

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“…On the other side, there are both over-diagnosis and overtreatment risks [3,4] Magnetic resonance imaging (MRI) provides excellent high-contrast, highresolution images of the prostate. In recent years, functional techniques have been applied in order to improve the performance of MRI in the diagnosis of prostate cancer [5][6][7][8]. Magnetic resonance spectroscopy (MRS) measures prostate metabolites concentrations, particularly choline and citrate, hat are respectively increased and reduced in cancer [6].…”

Section: Introductionmentioning

confidence: 99%

“…Magnetic resonance spectroscopy (MRS) measures prostate metabolites concentrations, particularly choline and citrate, hat are respectively increased and reduced in cancer [6]. Diffusion Weighted Image (DWI) provides water diffusion properties based imaging, with reduced water diffusion in highly cellular cancer tissues [5]. Early promising data suggest that multiparametric MRI (mpMRI), including morphologic sequences and functional MR approaches, may be of additional value for the localization of prostate cancer and its local staging [8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

A multiparametric MRI score for prostate cancer detection: Performance in patients with and without endorectal coil

Fusco¹,

Petrillo²,

Setola³

et al. 2018

Imaging-Medicine

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Purpose: To assess the diagnostic performance of multiparametric MRI (mpMRI), in the detection of prostate cancer in two different coil setting: endorectal coil (ERC) versus phased array coil alone (PAC). Materials and Methods: The study included 302 out of 395 consecutive patients with PSA values between 2.5-4 ng/ml and an abnormal Digital Rectal Examination (DRE), or patients with PSA values between 4-10ng/ml, independently from DRE. Each patient provided informed consent to undergo at serum free/total PSA ratio (f/t PSA) assay, morphological MRI (mMRI), DWI, MRS, and Trans Rectal Ultrasonography (TRUS) biopsy. The MRI data sets were scored singularly and then mMRI, DWI and MRS data were combined in a single score (cMRI score). cMRI score was correlated to negative biopsies and Gleason score biopsies. ROC curve and McNemar tests were performed. Results: cMRI score showed high value of sensitivity and NPV for both coil setting (84% and 93% respectively using ERC, 87% and 87% respectively using PAC). cMRI score using ERC did not show statistical superiority compared with cMRI score using PAC alone (p value at McNemar test > 0.05). A significant correlation was obtained comparing the cMRI score to the Gleason score for both coil conditions. Conclusions: Pelvic phased array coil imaging of the prostate produces high quality images and the overall performance in prostate cancer detection is equal than those obtained with endorectal coil imaging.

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T2- and diffusion-weighted magnetic resonance imaging at 3 T for the detection of prostate cancer with and without endorectal coil: An intraindividual comparison of image quality and diagnostic performance

Cited by 37 publications

References 19 publications

Diagnostic Accuracy of a MR Protocol Acquired with and without Endorectal Coil for Detection of Prostate Cancer: A Multicenter Study

Diagnostic Accuracy of a MR Protocol Acquired with and without Endorectal Coil for Detection of Prostate Cancer: A Multicenter Study

Cost consideration in utilization of multiparametric magnetic resonance imaging in prostate cancer

A multiparametric MRI score for prostate cancer detection: Performance in patients with and without endorectal coil

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