T1ρ Mri Assessment of Cartilage in a Large Animal Model of Traumatic Joint Injury

Abstract

ms. 5mm width of subchondral trabecular bone of the medial joint was extracted (figure), and divided into 4 subregions: anterior, center, posterior, and medial. Trabecular bone microstructure at each region was measured by the dedicated software (TRI/3D-BON, Ratoc System Engineering Co., Ltd., Tokyo). Results: BV/TV (bone volume fraction) at the anterior, center, posterior, and medial regions were 29.5, 29.6, 15.5, 34.2 % respectively. Tb.Th (trabecular thickness) were 285, 294, 245, 338 mm, Tb.N (trabecular number) were 0.64, 0.58, 0.65, 0.61 /mm, and Conn.D (connectivity density) were 2.33, 2.38, 1.15, 2.48. Conclusions: Subchondral bones were increased particularly at the medial region of the medial proximal tibia, composed of thickened and well-connected trabecular bones. Subchondral bone microstructure measured by HR-pQCT may become a new imaging marker for OA knees.