T143. Effect of anesthesia on electrocorticography for localization of epileptic focus: Literature review and future directions

Bayram, Ayşe Kaçar; Rao, Shilpa; Spencer, Dennis D.; Alkawadri, Rafeed

doi:10.1016/j.clinph.2018.04.144

Cited by 2 publications

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“…Compounding the short duration of sampling are the inhibitory effects of certain anesthetic agents on IEDs. 9 This trend in the use of iECoG might change due to the recent report by Chen et al 10 In an exploratory pilot study, the authors report on the use of pre-and post-LiTT iECoG as a predictor of seizure outcome in patients with mTLE. In this single-center cohort of 7 patients (5 with left mTLE, 2 with MTS, 4 studied with chronic iEEG), an 8-contact depth electrode was placed along the trajectory of the laser fiber used for eventual ablation of the amygdala and hippocampus posteriorly to the level of the mesencephalic sulcus.…”

Section: Commentarymentioning

confidence: 99%

Old Diagnostic Meets Newer Therapy; ECoG During LiTT

King-Stephens

2023

Epilepsy Curr

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Section: Commentarymentioning

confidence: 99%

Old Diagnostic Meets Newer Therapy; ECoG During LiTT

King-Stephens

2023

Epilepsy Curr

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“…A few studies have shown that dexmedetomidine has no or little activating effect on epileptiform activity (Chaitanya et al, 2015). Propofol, barbiturates, and benzodiazepines increase EEG background beta-sigma frequency-power and may obscure epileptiform discharges (Dahaba et al, 2013; Nishida et al, 2016; Bayram et al, 2018a).…”

Section: Current Standards and Recent Advances In Seizure Localizatiomentioning

confidence: 99%

“…Existing studies often do not employ common gold standard for localization, and the concept of pharmacological spike activation is challengeable. In our review of literature, of the five studies only provided specifics on site of resection and correlation with surgical outcomes out of 23 stduies reporting on spike activation of a total altogether 54 studies that met inclusion criteria (Bayram et al, 2018b).…”

Section: Current Bci Applications In Drug-resistant Epilepsymentioning

confidence: 99%

Brain–Computer Interface (BCI) Applications in Mapping of Epileptic Brain Networks Based on Intracranial-EEG: An Update

Alkawadri

2019

Front. Neurosci.

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The main applications of the Brain–Computer Interface (BCI) have been in the domain of rehabilitation, control of prosthetics, and in neuro-feedback. Only a few clinical applications presently exist for the management of drug-resistant epilepsy. Epilepsy surgery can be a life-changing procedure in the subset of millions of patients who are medically intractable. Recording of seizures and localization of the Seizure Onset Zone (SOZ) in the subgroup of “surgical” patients, who require intracranial-EEG (icEEG) evaluations, remain to date the best available surrogate marker of the epileptogenic tissue. icEEG presents certain risks and challenges making it a frontier that will benefit from optimization. Despite the presentation of several novel biomarkers for the localization of epileptic brain regions (HFOs-spikes vs. Spikes for instance), integration of most in practices is not at the prime time as it requires a degree of knowledge about signal and computation. The clinical care remains inspired by the original practices of recording the seizures and expert visual analysis of rhythms at onset. It is becoming increasingly evident, however, that there is more to infer from the large amount of EEG data sampled at rates in the order of less than 1 ms and collected over several days of invasive EEG recordings than commonly done in practice. This opens the door for interesting areas at the intersection of neuroscience, computation, engineering and clinical care. Brain–Computer interface (BCI) has the potential of enabling the processing of a large amount of data in a short period of time and providing insights that are not possible otherwise by human expert readers. Our practices suggest that implementation of BCI and Real-Time processing of EEG data is possible and suitable for most standard clinical applications, in fact, often the performance is comparable to a highly qualified human readers with the advantage of producing the results in real-time reliably and tirelessly. This is of utmost importance in specific environments such as in the operating room (OR) among other applications. In this review, we will present the readers with potential targets for BCI in caring for patients with surgical epilepsy.

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T143. Effect of anesthesia on electrocorticography for localization of epileptic focus: Literature review and future directions

Cited by 2 publications

References 0 publications

Old Diagnostic Meets Newer Therapy; ECoG During LiTT

Old Diagnostic Meets Newer Therapy; ECoG During LiTT

Brain–Computer Interface (BCI) Applications in Mapping of Epileptic Brain Networks Based on Intracranial-EEG: An Update

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