“…The pattern of predominant nocturnal symptoms differed from that of daytime symptoms. The prevalence of nocturnal symptoms in our participants was low compared with some reports 23 , although not all investigators found nocturnal symptoms to be common 24 . Our results were almost certainly influenced by inclusion of individuals with relatively mild symptoms, and it is also possible that our questionnaire did not reliably identify symptoms occurring during the ‘recumbent awake’ period, said to be especially important in reflux disease 25 .…”